Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Question
Chapter 8.2, Problem 1BC
Summary Introduction
To analyze:
The similarity and difference between the ligand binding to receptor and enzyme binding to the substrate.
Introduction:
A signal transduction pathway includes a group of proteins and polysaccharides that carry the signals by the binding of the signaling molecule with the receptor. The signals carried, leads to conformational changes in the proteins, further trigger a cascade of reactions leading to a cellular response.
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Chapter 8 Solutions
Principles of Biology
Ch. 8.1 - What is the signaling molecule in this example?Ch. 8.1 - Prob. 2CCCh. 8.1 - Prob. 3CCCh. 8.1 - A general reason for cell signaling is to respond...Ch. 8.1 - Prob. 2TYKCh. 8.1 - Prob. 3TYKCh. 8.2 - Prob. 1BCCh. 8.2 - Prob. 1TYKCh. 8.2 - Prob. 2TYKCh. 8.3 - Prob. 1CC
Ch. 8.3 - What has to happen for the a and subunits of the...Ch. 8.3 - Prob. 1TYKCh. 8.3 - After a G-protein-coupled receptor is activated,...Ch. 8.4 - Prob. 1TYKCh. 8.5 - Look ahead to Figures 13.9 and, in particular,...Ch. 8.5 - Prob. 1TYKCh. 8.5 - Prob. 2TYKCh. 8.6 - Prob. 1CCCh. 8.6 - Prob. 2CCCh. 8.6 - Prob. 3CCCh. 8.6 - Prob. 1TYKCh. 8.6 - Prob. 2TYKCh. 8 - Prob. 1TYCh. 8 - Prob. 2TYCh. 8 - Prob. 3TYCh. 8 - Prob. 4TYCh. 8 - Which of the following is not an example of a cell...Ch. 8 - Prob. 6TYCh. 8 - The EGF receptor functions as a receptor tyrosine...Ch. 8 - Prob. 8TYCh. 8 - Prob. 9TYCh. 8 - The benefit of second messengers in signal...Ch. 8 - Prob. 1CCQCh. 8 - Prob. 2CCQCh. 8 - Prob. 3CCQCh. 8 - Discuss and compare several different types of...Ch. 8 - Prob. 2CBQ
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- A ligand has difficulty binding to the binding site of an enzyme. What could this be due to? Group of answer options 1 a.The protein is tired bAnother protein has bound to the enzyme and altered its conformation cThe enzyme has been weighted incorrectly dAn amino acid in the binding pocket of the enzyme has been altered in a mutation eThe diffusion is too slow A competitive inhibitor has already bound into the binding pocket which are correctarrow_forwardTwo proteins bind the same ligand, and the data is shown below. Select the best answer based on this data: Protein A binds the ligand with higher affinity, as it has the highest KD value Protein B binds the ligand with higher affinity, as it has the lowest KD value Protein B binds the ligand with higher affinity, as it has the highest KD value Protein A binds the ligand with higher affinity, as it has the lowest KD valuearrow_forwardGive an example of how signal transduction plays a role in disease help this is a biochemistry for my last hw. he is very detailedarrow_forward
- During cell signaling, binding of a ligand to the outside of a cell leads to: A. A signal being sent inside the cell B. The ligand being transported into the cell C. A and B D. None of the abovearrow_forwardA signal peptide is found at the N-terminus of a newly generated protein's polypeptide chain. Which is not possible? Options: This protein is a sodium/potassium pump This protein is a membrane receptor This protein is the protein kinase A This protein is insulin This protein is an ion channelarrow_forwardThe molecule below is ATP. If you were to buy radioactively labeled ATP to use in making radiolabeled RNA, which phosphate (indicate with an arrow) would you want to have labeled with P32? If instead you were using ATP as a protein kinase substrate, which phosphate would you want to have labeled. Explain your reasoningarrow_forward
- Which is true about signaling receptors? They are transmembrane proteins that have binding sites for extracellular activated proteinsto effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular DNA-binding proteins to effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular enzyme effectors to effect changes inside the cell. They are transmembrane proteins that have binding sites for extracellular messengers to effect changes inside the cell.arrow_forwardIdentify which of the following statements is a lie? Select one: a. Protein kinase C can add a phosphate group in the hydroxyl groups of target proteins. b. PKC is involved in gene regulation. c. Protein kinase C directly activates cellular responses.arrow_forwardYou can choose one or more than one option The dissociation constant (Kd) of a receptor is: BIOCHEMISTRY basic the concentration of a ligand that produces 100% occupancy of the receptor the concentration of a ligand that produces 50% of the maximal effect. the measurement of specificity between ligand and its receptor. the measurement of speed by which a ligand will dissociate from its receptor. the measurement of affinity between a ligand and its receptor and the inverse of the association constant. During an experiment with Drosophila, it was discovered that all females had red eyes. unlike males. A conclusion based on this observation would be: MOLECULAR BIOLOGY basic The gene for eye color is located on the X chromosome. The females are homozygotes The gene for eye color is dominant. The eye color results from multigenic linkage. The eye color phenotype is sex-linked A secondary lysosome: CELL BIOLOGY advanced a lysosome that provides a backup to the primary…arrow_forward
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