Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 8, Problem 4TY
Summary Introduction

Introduction:

The signal molecules attach to the receptor and cause a cellular response. The signal molecules are proteins, also called a ligand, attaches non covalently to the receptor and activates it. The ligand and receptor need to collide at the correct angle and need enough energy to bind.

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when a chemical messenger (or ligand) reaches a target cell, it binds to a receptor.  A hydrophobic ligand binds to a(n) _______, whereas a hydrophilic ligand binds to a(n)_________.   a. agonist receptor; antagonic receptor   b. transmembrane receptor; intracellular receptor   c. antagonist receptor; agonist receptor   d. intracellular receptor; transmembrane receptor
You can choose one or more than one option    The dissociation constant (Kd) of a receptor is:    the concentration of a ligand that produces 100% occupancy of the receptor  the concentration of a ligand that produces 50% of the maximal effect.  the measurement of specificity between ligand and its receptor.  the measurement of speed by which a ligand will dissociate from its receptor.  the measurement of affinity between a ligand and its receptor and the inverse of the association constant.
Explain why a peptide (protein) ligand can’t use a receptor inside the cell while an asteroid has no problem using an intracellular receptor.
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