Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 8.1, Problem 2TYK
Summary Introduction

Introduction:

The holocrine cells or glands are formed from a specific type of cells that function to accumulate the product and then undergo disintegrations. The secretion produced from the holocrine glands is viscous in nature and consists of cellular fragments along with the fluid matter.

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A cell expresses a transmembrane protein that is cleaved at the plasma membrane to release an extracellular fragment. The fragment binds to receptor proteins on nearby cells and activates signaling pathways resulting in altered gene expression patterns in the cells. What form of intercellular signaling does this represent? Contact-dependent? Paracrine? Synaptic? Endocrine? Autocrine?
A cell releases a ligand that travels through the extracellular matrix to a nearby target cell. There, the ligand binds to a receptor on the target cells membrane. This is an example of _______ signaling using a _______ ligand.     paracrine ; hydrophobic     paracrine ; hydrophillic     endocrine ; hydrophobic     endocrine ; hydrophillic     autocrine ; hydrophobic     autocrine ; hydrophillic
. Hedgehog, the signal, does not travel very far to bind to its receptor, Patched, on target cells.Therefore, target cells that are closer to the signaling cell receive a stronger signal. What modeof signaling does this describe?A. EndocrineB. Paracrine/AutocrineC. SynapticD. Contact-dependentExplain:
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