Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 17, Problem 17QP
a.
Summary Introduction
To determine: The ABO genotype of the three individuals.
Introduction: The blood group of an individual is determined by the presence of a certain kind of antigen on the surface of blood cells. A, B, AB, and O are four major blood groups found in human beings. The determination of the blood type of an individual is essential before the process of blood transfusion.
b.
Summary Introduction
To determine: The conclusions made by the court during the paternity suit.
Introduction: The blood group of an individual is determined by the presence of a certain kind of antigen on the surface of blood cells. A, B, AB, and O are four major blood groups found in human beings. The determination of the blood type of an individual is essential before the process of blood transfusion.
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The following data were presented to a court during a paternity suit: a) the infant is a universal donor for blood transfusion; b) the mother bears antibodies against the B antigen only; c) the alleged father is a universal recipient in blood transfusion. Answer too questions:
- Can you identify the ABO genotype of the three individuals ?
- Can the court draw any conclusions ?
For this problem, use the information given in problem 14. A young woman with blood type O gave birth to a baby with blood type O. In a court case, she claims that a certain young man is the father of her child. The man has type A blood. Can he be the father? Can it be proven on this evidence alone that he is the father? Pls show work!
a) (i) What is the ABO blood group? (ii) Mention three importance of blood group test?
b) Write concisely on the biochemical genetics of the Human ABO Blood Group answering the following questions:
i) Who discovered the ABO blood group?
ii) What transfusions are safe between individuals with different blood groups in the ABO system
iii) the relationship between the ABO alleles and the antigens on the red blood cells
Chapter 17 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 17.8 - One treatment for peanut allergies is to give an...Ch. 17.8 - Prob. 2EGCh. 17 - Prob. 1CSCh. 17 - The Joneses were referred to a clinical geneticist...Ch. 17 - The Inflammatory Response Is a General a. What...Ch. 17 - The Complement System Kills Microorganisms The...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 4QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 6QP
Ch. 17 - Prob. 7QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 9QPCh. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - It is often helpful to draw a complicated pathway...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - The Adaptive Immune Response Is a Specific Defense...Ch. 17 - Prob. 14QPCh. 17 - Prob. 15QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 17QPCh. 17 - Blood Types Are Determined by Cell-Surface...Ch. 17 - Prob. 19QPCh. 17 - Prob. 20QPCh. 17 - Prob. 21QPCh. 17 - Organ Transplants Must Be Immunologically A burn...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically In the...Ch. 17 - Organ Transplants Must Be Immunologically A couple...Ch. 17 - Prob. 26QPCh. 17 - Disorders of the Immune System Antihistamines are...Ch. 17 - Disorders of the Immune System Autoimmune...Ch. 17 - Prob. 29QPCh. 17 - Prob. 30QPCh. 17 - Prob. 31QP
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- In the 1950s, A young woman sued film star/director Charlie Chaplin for parental support for her illegitimate child. Charlie Chaplin‘s blood type was already on record as type AB. The mother of the child had type B and her son had type O blood. The judge ruled in favor of the mother in order Charlie Chaplin to pay child-support cost for the child. Briefly explain why the judge was not correct in his decision based on blood typing evidence? arrow_forwardTwo mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?arrow_forwardA normal woman, whose father was a hemophiliac, marries a normal man. Determine the genotype of the woman and the man. Determine the possible genotypes of their children. What percent of male and female children would be hemophiliacs? What percent normal? Would any be carriers?arrow_forward
- Southern Blotting & Detection of sickle cell disease: Please interrupt the following results and draw a Punnett square, and answer the questions. •Discuss figures (gel figure and Punnett square) one by one. •You must provide discussion for each lane of the gel, how you make out normal, carrier, disease (allelic patterns- why so?), control IMPORTANT POINTS TO REMEMBER: •Homozygous (one band)- the size of the band (lower or higher in the gel) determines if normal (both alleles cut by MSt II, hence band lower) or diseased (both alleles uncut and hence at the higher position in gel) •Heterozygous (two bands in the same lane) denotes a carrier (lower band from normal allele which is cut by RE & upper sickle cell allele band is uncut)arrow_forwardblood typing is often used as evidence in paternity cases in the court of law. In one case, the mother had a blood type a and the child had a blood type O. Is it possible for the father to have blood type AB? Explain your reasoning.arrow_forwardDescribe how the Bombay phenotype is epistatic to the ABO blood phenotype in humans, and discuss some implications of this phenotype in blood typing and blood donation.arrow_forward
- Hemophilia is inherited as a sex-linked recessive trait. A non-hemophilic man marries a non-hemophilic woman whose father had hemophilia. With respect to this information, indicate all possible genotypes their children could possibly have. Show ALL work using punnett squares.arrow_forward, use the following information: type A hemophilia, a disorder in which blood does not clot properly, is governed by a recessive allele on the X chromosome. Suppose a healthy woman is a carrier and marries a man with hemophilia A, and they are expecting a child. Use XH = normal clotting, Xh = hemophilia. What is the chance the child will be male? What is the chance the child will be a male with hemophilia? What is the chance the child will be a female with hemophilia?arrow_forwardCodominance: draw a Punnett Square for a AA mom with a AB dad. i. If you have type AB blood type, what possible blood types could your parents have? ii. If you have type A blood, can either of your parents have type O? iii. If you have type O blood, could either of your parents be type AB? Upload your image using the paperclip iconarrow_forward
- Blood types in humans are Codominant. a. What are the possible genotypes of someone with type O blood? b. What are the possible genotypes of someone with type B blood? c. What is the phenotype of someone’s whose genotype is AO? d. A man with AB blood is married to a woman with AB blood. What blood types will their children be and in what proportion?arrow_forwardIn a paternity suit, a woman with type O blood claims that a man with type AB blood is the father of her type O baby. List the genetypes of the mom, man, and baby. Can the woman prove he is the father or can he is not? Why or why not? If the accused man was type A insyead of type AB, what would be his possible genotypes? Could the woman prove he is the father? Can the man prove he is not the father? Why or why not?arrow_forwardExplain the ABO blood system as an example of multiple alleles and codominance; be sure to discuss blood phenotype as an expression of surface proteins, “markers” on the red blood cellsarrow_forward
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