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Organ Transplants Must Be Immunologically A couple has a young child who needs a bone marrow transplant. They propose that preimplantation screening be done on several embryos fertilized in vitro to find a match for their child. a. What do they need to match in this transplant procedure? b. The couple proposes that the matching embryo be transplanted to the mother’s uterus and serve as a bone marrow donor when old enough. What are the ethical issues involved in this proposal?

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 17, Problem 25QP
Textbook Problem
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Organ Transplants Must Be Immunologically

A couple has a young child who needs a bone marrow transplant. They propose that preimplantation screening be done on several embryos fertilized in vitro to find a match for their child.

  1. a.           What do they need to match in this transplant procedure?
    1. b.          The couple proposes that the matching embryo be transplanted to the mother’s uterus and serve as a bone marrow donor when old enough. What are the ethical issues involved in this proposal?

a.

Summary Introduction

To determine: The test that must be done to match the compatibility of the transplanted organ.

Introduction: The immune system of the body can differentiate between self and non-self antigens. A successful organ transplant requires the matching between cell-surface antigen of recipient and donor.

Explanation of Solution

A couple had a young child that requires bone marrow transplantation. For the bone marrow transplantation, some preimplantation screening test must be done to identify the desired match for their child. The preimplantation test is important for successful bone marrow transplantation.

The first test that is important to determine the compatibility of bone marrow is ABO blood type. The donor must have identical blood type as that of the recipient. The second test involves the presence of Rh factor...

b.

Summary Introduction

To determine: The ethical issues involved in implanting the matching embryo in the mother’s uterus which can become a bone marrow donor.

Introduction: The immune system of the body can differentiate between self and non-self antigens. A successful organ transplant requires the matching between cell-surface antigen of recipient and donor.

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