Concept explainers
a.
To determine:
The expression that describes the equilibrium frequencies for all the genotypes in men and women.
Introduction:
The concept of Hardy-Weinberg equilibrium was introduced by a scientist named Geoffrey H. Hardy. The equilibrium frequencies for men and women can be calculated separately by using the concept of Hardy-Weinberg equilibrium.
b.
To determine:
The proportion of American females would be hemophiliacs. The number of female hemophiliacs can be found among 170 million women residing in the United States.
Introduction:
The disease in which blood lacks clotting proteins is termed as hemophilia. It is a severe disorder as the body is unable to clot the injured tissues. The blood keeps on mobbing out of the body from the site of injury. Hemophilia can also lead to the death of a person in serious cases. It has been observed that one out of every ten thousand males in the United States suffers from hemophilia.
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Genetics: From Genes to Genomes, 5th edition
- stion 6 of 18 Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver. She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F, females in a testcross. She obtains the flies from this testcross. Phenotype Number of flies vg* qu+ 230 vg qu 224 vg qut vg* qu 97 99 Test the hypothesis that the genes quiver and vestigial assort independently by calculating the chi-squared, X², for this hypothesis. Provide the X2 to one decimal place. X2 = Does the X value support the hypothesis that the quiver and vestigial genes assort independently? Why or why not? the partial table of critical values for X2 calculations to test this hypothesis.arrow_forwarda. Two linked biallelic loci (c = 0.1) have allele frequencies pA = 0.7 and pB = 0.4. If these two sites are in linkage disequilibrium with D = -0.12, what are the expected haplotype frequencies under these conditions? b. What will the linkage disequilibrium parameter D be after 20 generations?arrow_forwardGive the genotypic frequencies expected under the Hardy–Weinberg law for (a) an autosomal locus with three alleles and (b) an X-linked locus with two alleles.arrow_forward
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