Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 20, Problem 12P
Summary Introduction

a.

To determine:

The expression that describes the equilibrium frequencies for all the genotypes in men and women.

Introduction:

The concept of Hardy-Weinberg equilibrium was introduced by a scientist named Geoffrey H. Hardy. The equilibrium frequencies for men and women can be calculated separately by using the concept of Hardy-Weinberg equilibrium.

Summary Introduction

b.

To determine:

The proportion of American females would be hemophiliacs. The number of female hemophiliacs can be found among 170 million women residing in the United States.

Introduction:

The disease in which blood lacks clotting proteins is termed as hemophilia. It is a severe disorder as the body is unable to clot the injured tissues. The blood keeps on mobbing out of the body from the site of injury. Hemophilia can also lead to the death of a person in serious cases. It has been observed that one out of every ten thousand males in the United States suffers from hemophilia.

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Students have asked these similar questions
(b). The S-s antigen system in human is controlled by two codominant alleles, S and s. In a group of 3146 individuals, the following genotypic frequencies were found: 188 SS, 717 Ss, and 2241 ss. Calculate the frequency of s. O q = 0.8263 O q = 0.9402 O q = 0.4701 O q = 0.1438
Give nine examples of lethal alleles in humans, other animals, and plants and a brief molecular explanation (i.e., why are they lethal).
Hemophilia A is caused by a sex-linked recessive gene in human and in dogs. a. What proportions (and sexes), among their offspring will be hemophiliacs if a hemophilic male is mated to a homozygous nonhemophilic female?b. If a daughter produced by the mating in (a) is mated to a normal male, what proportions and (sexes) will be hemophilic among their offspring?

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Genetics: From Genes to Genomes, 5th edition

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