Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 20, Problem 14P
Summary Introduction

a.

To determine:

An equation that describes the equilibrium proportions of genotypes for a gene with three alleles.

Introduction:

The set of the alleles in DNA that carries the information for the expression of a trait in an individual is known as its genotype. For example, genotype ‘TT’ expresses the tallness in plants.

Summary Introduction

b.

To determine:

The frequencies of individuals with the four possible blood types.

Introduction:

There are four possible blood groups. These are A, B, AB and O. The alleles that code for ABO blood groups are IA, IB, and i. The allele IA codes for blood group A, IB codes for blood group B and i do not code for any blood group. i allele is found in O blood group. The AB blood group has both IA and IB alleles.

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The equation p + 2pq + q = 1 representing the Hardy-Weinberg proportions examines genes with only two alleles in a population. a. Derive a similar equation describing the equilib- rium proportions of genotypes for a gene with three alleles. [Hint: Remember that the Hardy- Weinberg equation can be written as the binomial expansion (p + q)*.] b. A single gene with three alleles (r, 1", and i) is responsible for the ABO blood groups. Individuals with blood type A can be either A or ^ i; those with blood type B can be either /* 1 or * i; people with AB blood are r*, and type O individuals are ii. Among Armenians, the frequency of ^ is 0.360, the frequency of 1 is 0.104, and the frequency of i is 0.536. Calculate the frequencies of individuals in this population with the four possible blood types, assuming Hardy-Weinberg equilibrium. %3D
The equation p2+ 2pq + q2= 1 representing theHardy-Weinberg proportions examines genes withonly two alleles in a population.a. Derive a similar equation describing the equilibrium proportions of genotypes for a gene withthree alleles. [Hint: Remember that the HardyWeinberg equation can be written as the binomialexpansion (p + q)2.]b. A single gene with three alleles (IA, IB, and i) isresponsible for the ABO blood groups. Individualswith blood type A can be either IA IAor IA i;those with blood type B can be either IB IBor IB i;people with AB blood are IA IB, and type O individuals are ii. Among Armenians, the frequency of IAis0.360, the frequency of IBis 0.104, and the frequencyof i is 0.536. Calculate the frequencies of individuals in this population with the four possible bloodtypes, assuming Hardy-Weinberg equilibrium.In Problems 15–17, you will see that because matingbetween individuals within populations at Hardy-Weinbergequilibrium is random, it is possible to predict…
Example 3.5.7 Fish Vertebrae Consider the distribution of vertebrae given in Table 3.5.1. In Exam- ple 3.5.5 we found that the mean of Y is µy = 21.49. The variance of Y is VAR(Y) = of = (20 – 21.49) x Pr{Y = 20} 21) %3D + (21 – 21.49)? x Pr{Y + (22 – 21.49)? x Pr{Y = 22} + (23 – 21.49) x Pr{Y = 23} = (-1.49) x 0.03 + (-.49) x 0.51 + (0.51) x 0.40 + (1.51)² × 0.06 = 2.2201 x 0.03 + .2401 x 0.51 + .2601 x 0.40 + 2.2801 x 0.06 = 0.066603 + 0.122451 + 0.10404 + 0.136806 = 0.4299. The standard deviation of Y is ay = V0.4299 - 0.6557. %3D

Chapter 20 Solutions

Genetics: From Genes to Genomes, 5th edition

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