Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 20, Problem 16P
Some people can taste the bitter compound phenylthiocarbamide while others cannot. This trait is governed by a single autosomal gene; the allele for tasting is completely dominant with respect to the allele for nontasting. Among 1707 Hawaiians tested for the ability to taste, 1326 tasters were found. Assuming that the population is at Hardy-Weinberg equilibrium for this gene and that mating is purely random:
| a. | What are the allele frequencies for the tasting allele T [= (p)] and for the nontasting allele t [= (q)]? |
| b. | What are the genotype frequencies in the population? |
| c. | Of all the matings in the population, what proportion will be between two nontasters? |
| d. | Of all the matings in the population, what proportion will be between a taster and a nontaster? |
| e. | Of all the matings in the population, what proportion will be between a taster male and a nontaster female? |
| f. | What proportion of all of the progeny produced by all matings between a taster male and a nontaster female will be nontasters? |
| g. | Of all the matings in the population, what proportion will be between two tasters? |
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The ability to taste the chemical compound PTC (phenylthiocarbamide) is coded for by a single gene with two alleles. Let T stand for the allele that codes for tasting and t for the allele that codes for non-tasting. This allele exhibits complete dominance, such that heterozygotes can also taste PTC. Suppose that out of a population of 100 students, 70 are tasters. Estimate the allele frequencies and the frequencies of TT, Tt and tt genotypes in the population. Show all your work, and clearly state your logic and any assumptions you make in estimating the frequencies
Chapter 20 Solutions
Genetics: From Genes to Genomes, 5th edition
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