Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 20, Problem 6P

A dominant mutation in Drosophila called Delta causes changes in wing morphology in Delta / + heterozygotes. Homozygosity for this mutation (Delta / Delta) is lethal. In a population of 150 flies, it was determined that 60 had normal wings and 90 had abnormal wings.

a. What are the allele frequencies in this population?
b. Using the allele frequencies calculated in part (a), how many total zygotes must be produced by this population in order for you to count 160 viable adults in the next generation?
c. Given that there is random mating, no migration, and no mutation, and ignoring the effects of genetic drift, what are the expected numbers of the different genotypes in the next generation if 160 viable offspring of the population in part (a) are counted?
d. Is this next generation at Hardy-Weinberg equilibrium? Why or why not?
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Genetics: From Genes to Genomes, 5th edition

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