Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 20, Problem 11P

It is the year 1998, and the men and women sailors (in equal numbers) on the American ship the Medischol Bounty have mutinied in the South Pacific and settled on the island of Bali Hai, where they have come into contact with the local Polynesian population. Of the 400 sailors that come ashore on the island, 324 have MM blood type, 4 have the NN blood type, and 72 have the MN blood type. Already on the island are 600 Polynesians between the ages of 19 and 23. In the Polynesian population, the allele frequency of the M allele is 0.06, and the allele frequency of the N allele is 0.94. No other people come to the island over the next 10 years.

a. What is the allele frequency of the N allele in the sailor population that mutinied?
b. It is the year 2008, and 1000 children have been born on the island of Bali Hai. If the mixed population of 1000 young people on the island in 1998 mated randomly and the different blood group phenotypes had no effect on viability, how many of the 1000 children would you expect to have MN blood type?
c. In fact, 50 children have MM blood type, 850 have MN blood type, and 100 have NN blood type. What is the observed frequency of the N allele among the children?
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It is the year 1998, and the men and women sailors (inequal numbers) on the American ship the MedischolBounty have mutinied in the South Pacific and settledon the island of Bali Hai, where they have come intocontact with the local Polynesian population. Of the400 sailors that come ashore on the island, 324 haveMM blood type, 4 have the NN blood type, and 72 havethe MN blood type. Already on the island are 600Polynesians between the ages of 19 and 23. In thePolynesian population, the allele frequency of the Mallele is 0.06, and the allele frequency of the N allele is 0.94. No other people come to the island over thenext 10 years.a. What is the allele frequency of the N allele in thesailor population that mutinied?b. It is the year 2008, and 1000 children have beenborn on the island of Bali Hai. If the mixed population of 1000 young people on the island in 1998mated randomly and the different blood groupphenotypes had no effect on viability, how manyof the 1000 children would you expect…
Tristan da Cunha is a group of small islands in themiddle of the Atlantic Ocean. In 1814, a group of 15British colonists founded a settlement on these islands.In 1885, 15 of the 19 males on the island were lost ina shipwreck. In the late 1960s, four cases of retinitispigmentosa, which progressively leads to blindness,were found among the 240 descendants of these settlers remaining on the island. The frequency of retinitis pigmentosa in Britain is about 1 in 6000. Explainthe high incidence of this disease on Tristan daCunha relative to that seen in Britain.
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Genetics: From Genes to Genomes, 5th edition

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