EBK ORGANIC CHEMISTRY
EBK ORGANIC CHEMISTRY
6th Edition
ISBN: 8220103151757
Author: LOUDON
Publisher: MAC HIGHER
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Chapter 26, Problem 26.44AP
Interpretation Introduction

Interpretation:

The given compounds are to be arranged in increasing order reactivity towards amide hydrolysis in NaOH.

Concept introduction:

The hydrolysis of amide in the presence of NaOH result in the breakdown of amide linkage into carboxylic acid and amine molecule. This hydrolysis reaction is slower than the ester hydrolysis reaction. Due to this heating condition is required.

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(a) Which is more reactive towards Electrophilic aromatic substitution (EAS)? (b) Which of the following is a a meta-substituted compound? (c) Which is the least reactive towards Electrophilic aromatic substitution (EAS)? (d) Which is an ortho-substituted compound?
Give a clear handwritten answer with explanation...complete the following reactions with explanation
(b) Distinguish each as aromatic or antiaromatic in terms of electronic basis. Explain which one is more stable. (i) Compound A Compound B (ii) Compound C Compound D (iii) Compound E Compound F
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