Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Videos
Question
Chapter 8, Problem 122P
To determine
Check whether the mean changes in weight in the intervention group.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
In its January 25, 2012, issue, the Journal of the American Medical Association reported on the effects of overconsumption of low, normal, and high protein diets on weight gain, energy expenditure, and body composition. Researchers conducted a single blind, randomized controlled trial of 25 U.S. adults. The subjects were healthy, weight-stable, male and female volunteers, aged 18 to 35 years. All subjects consumed a weight-stabilizing diet for 13 to 25 days. Afterwards, the researchers randomly assigned participants to diets containing various percentages of energy from protein: 5% (low protein), 15% (normal protein), or 25% (high protein). The subjects were not aware of the specific protein level diet to which they were assigned. On these diets the researchers overfed the participants during the last 8 weeks of their 10 to 12 week stay in the inpatient metabolic unit. The goal was to investigate the effect of overconsumption of protein on weight gain, energy expenditure, and body…
An article from the American Journal of Public Health reports the results from a randomized study designed to evaluate the efficacy of an intervention targeted to Hispanic/Latino men who identify as gay, bi-sexual or other men who have sex with men (MSM).
A representative sample of 254 such men was randomized to be in either the intervention group (n=152, with 141 ultimately participating in the study) or the control group (n=152, with 147 ulitmately participating in the study). The primary outcome under study getting tested for HIV within the six-months following group assignment (randomization) among those who had been sexually active in this same six-month follow-up period.
At six months of follow-up, 141 subjects in the intervention group reported having had sex (with men and/or women) since randomization. Of these 141 men, 114 had been tested for HIV since being randomized.
At six months of follow-up, 147 subjects in the control group reported having had sex (with men…
The Physicians' Health Study was a randomized clinical trial, one goal of which was to assess the effect of aspirin in preventing myocardial infarction (MI). Participants were 22,000 male physicians ages 40-84 and free of cardiovascular disease in 1982. The physicians were randomized to either active aspirin (one white pill containing 325 mg of aspirin taken every other day) or aspirin placebo (one white placebo pill taken every other day).
Suppose we assume that the incidence of MI is 0.005 per year among participants who actually take placebo and that aspirin prevents 20% of MIs.
How many participants need to be enrolled in each group to have an **80%** chance of detecting a significant difference using a **one-sided test** with $\alpha=0.05$ if **compliance is perfect**?
Chapter 8 Solutions
Fundamentals of Biostatistics
Ch. 8 - Find the lower 2.5th percentile of an F...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...
Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - Refer to the data in Table 2.13. Table 2.13...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. Perform the...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. Compute a 95% CI...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - A study in Pittsburgh measured various...Ch. 8 - A study in Pittsburgh measured various...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - Prob. 31PCh. 8 - Prob. 32PCh. 8 - Prob. 33PCh. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - Prob. 38PCh. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - A study was conducted of genetic and environmental...Ch. 8 - A study was conducted of genetic and environmental...Ch. 8 - Prob. 51PCh. 8 - Prob. 52PCh. 8 - Prob. 53PCh. 8 - Prob. 54PCh. 8 - Prob. 55PCh. 8 - Prob. 56PCh. 8 - Prob. 57PCh. 8 - Prob. 58PCh. 8 - Prob. 59PCh. 8 - Prob. 60PCh. 8 - Prob. 61PCh. 8 - Prob. 62PCh. 8 - Prob. 63PCh. 8 - A study was conducted [12] comparing muscle...Ch. 8 - Prob. 65PCh. 8 - A clinical trial compared percutaneous...Ch. 8 - Prob. 68PCh. 8 - Prob. 69PCh. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - Prob. 73PCh. 8 - Prob. 74PCh. 8 - Prob. 75PCh. 8 - Prob. 77PCh. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - Prob. 81PCh. 8 - Prob. 82PCh. 8 - Prob. 83PCh. 8 - Tennis elbow is a painful condition that afflicts...Ch. 8 - Prob. 85PCh. 8 - Prob. 86PCh. 8 - Prob. 87PCh. 8 - Prob. 88PCh. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - Prob. 94PCh. 8 - Prob. 95PCh. 8 - Prob. 96PCh. 8 - Prob. 98PCh. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - Prob. 105PCh. 8 - Prob. 106PCh. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Prob. 109PCh. 8 - Prob. 110PCh. 8 - Prob. 111PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - Prob. 113PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - The Diabetes Prevention Study was a randomized...Ch. 8 - Prob. 122PCh. 8 - Prob. 123PCh. 8 - Prob. 124PCh. 8 - Prob. 125PCh. 8 - Prob. 126PCh. 8 - Prob. 127PCh. 8 - A study looked at the influence of retirement on...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Prob. 134PCh. 8 - Prob. 135PCh. 8 - Prob. 136PCh. 8 - Prob. 137PCh. 8 - Prob. 138PCh. 8 - Prob. 142PCh. 8 - Prob. 143PCh. 8 - Prob. 144PCh. 8 - Prob. 145PCh. 8 - A study of genetic factors related to coronary...Ch. 8 - A study of genetic factors related to coronary...Ch. 8 - A study of genetic factors related to coronary...Ch. 8 - Prob. 149PCh. 8 - Prob. 150PCh. 8 - Prob. 151PCh. 8 - Prob. 152PCh. 8 - Prob. 153PCh. 8 - Prob. 154PCh. 8 - Prob. 155PCh. 8 - An individual has been exercising at a local gym...Ch. 8 - Prob. 157PCh. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - The following data are from a study on Botox...Ch. 8 - The following data are from a study on Botox...Ch. 8 - Prob. 166PCh. 8 - Prob. 167PCh. 8 - Prob. 168PCh. 8 - The EPIC-Norfolk study, a study of diet and cancer...Ch. 8 - Prob. 170PCh. 8 - Prob. 171PCh. 8 - Prob. 172PCh. 8 - Prob. 173PCh. 8 - Prob. 174PCh. 8 - Prob. 175PCh. 8 - Prob. 176P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.Similar questions
- The article “Treadmill Exercise and Resistance Training in Patients With Peripheral Arterial Disease With and Without Intermittent Claudication. A Randomized Controlled Trial” (M. McDermott, P. Ades, et al., Journal of the American Medical Association, 2009:165–174) reported the results of a study to determine whether treadmill exercise could improve the walking ability of patients suffering from claudication, which is pain caused by insufficient blood flow to the muscles of the legs. A sample of 48 patients walked on a treadmill for six minutes every day. After six months, the mean distance walked in six minutes was 348 m, with a standard deviation of 80 m. For a control group of 46 patients who did not walk on a treadmill, the mean distance was 309 m with a standard deviation of 89 m. Find a 95% confidence interval for the difference in mean distance walked between the two groups of patients.arrow_forwardThe article “Treadmill Exercise and Resistance Training in Patients With Peripheral Arterial Disease With and Without Intermittent Claudication. A Randomized Controlled Trial” (M. McDermott, P. Ades, et al., Journal of the American Medical Association, 2009:165–174) reported the results of a study to determine whether treadmill exercise could improve the walking ability of patients suffering from claudication, which is pain caused by insufficient blood flow to the muscles of the legs. A sample of 48 patients walked on a treadmill for six minutes every day. After six months, the mean distance walked in six minutes was 348 meters, with a standard deviation of 80 m. For a control group of 46 patients who did not walk on a treadmill, the mean distance was 309 m with a standard deviation of 89 m. Can you conclude that the mean distance walked for patients using a treadmill is greater than the mean for the controls? Use the α = 0.05 level of significance.arrow_forwardIn randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 116 of 651 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 73 of 532 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the α=0.10 level of significance? #1 Find the test statistic for this hypothesis test.arrow_forward
- In randomized, double-blind clinical trials of a new vaccine, infants were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 126 of 387 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 158 of 574 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α=0.01 level of significance? Verify the model requirements. Select all that apply. A. The sample size is less than 5% of the population size for each sample. B. n1p11−p1≥10 and n2p21−p2≥10 C. The samples are dependent. D. The sample size is more than 5% of the population size for each sample. E. The samples are independent. F. The data come…arrow_forwardElizon Pharmaceuticals, Inc., announced the results of its first human trial of NPI 32101, a topical form of its skin ointment. A total of 225 patients diagnosed with skin irritations were randomly divided into three groups as part of a double-blind, placebo-controlled study to test the effectiveness of the new topical cream. The first group received a 0.5% cream, the second group received a 1.0% cream, and the third group received a placebo. Groups were treated twice daily for a 6-week period. (a)What type of experimental design is this? (b)What is the control group for this study? (c)What is the factor that is set to predetermined levels? What is the treatment? (d)What does it mean for this study to be double-blind? (e)Identify the experimental units. (f)Draw a diagram to illustrate the design.arrow_forwardIn a randomized double-blind clinical trials of a new vaccine children were randomly divided into two groups subjects in group one received the new vaccine while subjects in group 2 received a control vaccine after the second dose 112 of 690 subjects in the experimental group 1 experienced drowsiness as a side effect after the second dose 69 of 571 of the subjects in the control group 2 experienced drowsiness as a side effect does the evidence suggest that a higher proportion of subjects in group 1 experience drowsiness as a side effect than subjects in group 2 at 0.05 level of significance? Determine the null and alternative hypothesis? find the test statistic for this hypothesis test? determine the P value for this hypothesis test? do we reject or not reject the null hypothesis and why? State your conclusion?arrow_forward
- A 2017 article in The New England Journal of Medicine details the results of a randomized clinical trial designed to evaluate the efficacy of a rotavirus gastroenteritis vaccine designed for infants. As per the authors: “Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in sub-Saharan Africa. We conducted a randomized, placebo-controlled trial in Niger to evaluate the efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) to prevent severe rotavirus gastroenteritis. Healthy infants received three doses of the vaccine or placebo at 6, 10, and 14 weeks of age. Episodes of rotavirus gastroenteritis were assessed through active and passive surveillance.” The following Kaplan-Meier curves show the time to a diagnosis of rotavirus gastroenteritis separately for the vaccine and placebo samples. Infants were followed for up to 60…arrow_forwardThe Joint Commission on Accreditation of Healthcare Organizations mandated that hospitals ban smoking by 1994. To study the effects of this ban on smoking behaviors, subjects were randomly selected from two different populations: those from hospitals with the ban and those from hospitals without the ban. Investigators were interested in determining if this smoking ban had any impact on the proportion of smokers employed at each hospital that then quit smoking. Let px be the proportion of smokers from hospitals that implemented the ban who quit smoking during the study period. Let py be the proportions of smokers from hospitals without the ban who quit smoking during the study period. Please select the appropriate hypotheses. H0: px = 0.50 HA: px ≠ 0.50 H0: px-py ≥ 0 HA: px-py H0: px-py ≤ 0 HA: px-py > 0 H0: px-py = 0 HA: px-py ≠ 0arrow_forwardIn a study conducted in the Science Department of Faculty of Science, Technology and Human Development in a University; the researcher examined the influence of the drug succinylcholine on the circulation levels of androgens in the blood. Blood samples from wild, free-ranging deer were obtained via the jugular vein immediately after an intramuscular injection of succinylcholine using darts and a capture gun. Deer were bled again approximately 30 minutes after the injection and then released. The level of androgens at time of capture and 30 minutes later, measured in nanograms per milliliter (ng/ml), for 15 deers as in Table Q1. Assuming that the populations of androgen at time of injection and 30 minutes later are normally distributed:i) Find the average and standard deviation of this studyii)Determine the critical region of this problem.iii) Test at the 0.05 level of significance whether the androgen concentrations are altered after 30 minutes of restraint.arrow_forward
- A hospital conducted a study of the waiting time in its -emergency room. The hospital has a main campus and three -satellite locations. Management had a business objective of reducing waiting time for emergency room cases that did not require immediate attention. To study this, a random sample of 15 emergency room cases that did not require immediate attention at each location were selected on a particular day, and the waiting times (measured from check- in to when the patient was called into the clinic area) were collected and stored in the table. a) At the 0.05 level of significance, is there evidence of a difference in the mean waiting times in the four locations? Main Satellite 1 Satellite 2 Satellite 3 120.08 30.75 75.86 54.05 81.90 61.83 37.88 38.82 78.79 26.40 68.73 36.85 63.83 53.84 51.08 32.83 79.77 72.30 50.21 52.94 47.94 53.09 58.47 34.13 79.88 27.67 86.29 69.37 48.63 52.46 62.90 78.52 55.43 10.64 44.84 55.95 64.06 53.50 64.17 49.61 64.99 37.28…arrow_forwardA consumer advocacy group wanted to study whether different airline carriers differed in terms of their delayed flights. In particular, the researchers were interested in the relationship between p1, the proportion of Alpha Airlines flights that were delayed at least 15 minutes, and p2, the proportion of Beta Airlines flights that were delayed at least 15 minutes. A random sample of 1,000 Alpha flights and a separate random sample of 1,000 Beta flights found that 67 of the Alpha fights and 160 of the Beta flights were delayed at least 15 minutes. The conditions for inference were checked and verified. Does this set of samples provide strong evidence that Alpha Airlines has a smaller proportion of flights that are delayed at least 15 minutes than Beta Airlines, at the α = 0.05 significance level? Find the z-table here. A. The test statistic is z = –6.56 and the P-value ≈ 0. Since the P-value ≈ 0 < 0.05, there is not sufficient evidence that Alpha Airlines has fewer delayed…arrow_forwardThe researchers sought to explore the connection between dietary fat consumption and the incidence of cardiovascular disease (CVD) events in a cohort of 5,115 young adults of both Black and White backgrounds. In 1985, these individuals underwent an initial examination. Over the subsequent 35 years, those who were initially free of disease were monitored to investigate the potential associations between their dietary fat intake and the occurrence of CVD events. Among the 2,100 young adults who had a high-fat diet at the start of the study, 255 experienced a new CVD event. Among the 3,015 young adults who did not have a high-fat diet at baseline, 125 experienced a new CVD event during the follow-up period. Risk of CVD events among those with a high-fat diet is ____. Risk of CVD events among those without a high-fat is ____. The relative risk is ____.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Holt Mcdougal Larson Pre-algebra: Student Edition...AlgebraISBN:9780547587776Author:HOLT MCDOUGALPublisher:HOLT MCDOUGAL
Holt Mcdougal Larson Pre-algebra: Student Edition...
Algebra
ISBN:9780547587776
Author:HOLT MCDOUGAL
Publisher:HOLT MCDOUGAL
Introduction to experimental design and analysis of variance (ANOVA); Author: Dr. Bharatendra Rai;https://www.youtube.com/watch?v=vSFo1MwLoxU;License: Standard YouTube License, CC-BY