Fundamentals of Biostatistics
Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 8, Problem 129P

Cigarette smoking has important health consequences and is positively associated with heart and lung diseases. Less well known are the consequences of quitting smoking. A group of 10 nurses, from the Nurses’ Health Study, ages 50−54 years, had smoked at least 1 pack per day and quit for at least 6 years. The nurses reported their weight before and 6 years after quitting smoking. A commonly used measure of obesity that takes height and weight into account is BMI = wt/ht2 (in units of kg/m2). The BMI of the 10 women before and 6 years after quitting smoking are given in the last 2 columns of Table 8.32.

Table 8.32 BMI change in 50- to 54-year-old women over a 6-year period

Chapter 8, Problem 129P, Cigarette smoking has important health consequences and is positively associated with heart and lung

What test can be used to assess whether the mean BMI changed significantly among heavy-smoking women 6 years after quitting smoking?

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A group of 10-year-old boys were first ascertained in a camp for diabetic boys. They had their weight measured at baseline and again when they returned to camp 1 year later. Each time, a serum sample was obtained from which a determination of hemoglobin A1c (HgbA1c) was made. HgbA1c (also called glycosylated hemoglobin) is routinely used to monitor compliance with taking insulin injections. Usually, the poorer the compliance, the higher the HgbA1c level will be. The hypothesis is that the level HgbA1c is related to weight. The data in Table 11.28 were obtained. 11.95 Compute a rank correlation between change in weight and change in HgbA1c, each over 1 year. Use this measure to directly test the hypothesis that change in weight over 1 year is related to change in HgbA1c. Report a two-tailed p-value, and provide a 95% confidence interval for the underlying rank correlation.
A group of 10-year-old boys were first ascertained in a camp for diabetic boys. They had their weight measured at baseline and again when they returned to camp 1 year later. Each time, a serum sample was obtained from which a determination of hemoglobin A1c (HgbA1c) was made. HgbA1c (also called glycosylated hemoglobin) is routinely used to monitor compliance with taking insulin injections. Usually, the poorer the compliance, the higher the HgbA1c level will be. The hypothesis is that the level HgbA1c is related to weight. The data in Table 11.28 were obtained.11.92 What test can be performed to assess the relationship between weight and HgbA1c at the initial visit?11.93 Please perform the test in Problem 11.92, and report a two-tailed p-value.11.94 Do the results in Problem 11.93 imply a relationship between change in HgbA1c and change in weight for an individual boy? Why or why not?11.95 Compute a rank correlation between change in weight and change in HgbA1c, each over 1 year. Use…

Chapter 8 Solutions

Fundamentals of Biostatistics

Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - The mean 1 sd of ln [calcium intake (mg)] among 25...Ch. 8 - Refer to the data in Table 2.13. Table 2.13...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. Perform the...Ch. 8 - Refer to the data in Table 2.13. What is the...Ch. 8 - Refer to the data in Table 2.13. Compute a 95% CI...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - The drug diflunisal is used to treat mild to...Ch. 8 - A study in Pittsburgh measured various...Ch. 8 - A study in Pittsburgh measured various...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A 1980 study was conducted whose purpose was to...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - A camera has been developed to detect the presence...Ch. 8 - Prob. 31PCh. 8 - Prob. 32PCh. 8 - Prob. 33PCh. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - A possible important environmental determinant of...Ch. 8 - Prob. 38PCh. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - The degree of clinical agreement among physicians...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - Ten patients with advanced diabetic nephropathy...Ch. 8 - A study was conducted of genetic and environmental...Ch. 8 - A study was conducted of genetic and environmental...Ch. 8 - Prob. 51PCh. 8 - Prob. 52PCh. 8 - Prob. 53PCh. 8 - Prob. 54PCh. 8 - Prob. 55PCh. 8 - Prob. 56PCh. 8 - Prob. 57PCh. 8 - Prob. 58PCh. 8 - Prob. 59PCh. 8 - Prob. 60PCh. 8 - Prob. 61PCh. 8 - Prob. 62PCh. 8 - Prob. 63PCh. 8 - A study was conducted [12] comparing muscle...Ch. 8 - Prob. 65PCh. 8 - A clinical trial compared percutaneous...Ch. 8 - Prob. 68PCh. 8 - Prob. 69PCh. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - An experiment was conducted to examine the...Ch. 8 - Prob. 73PCh. 8 - Prob. 74PCh. 8 - Prob. 75PCh. 8 - Prob. 77PCh. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - A study was performed looking at the effect of...Ch. 8 - Prob. 81PCh. 8 - Prob. 82PCh. 8 - Prob. 83PCh. 8 - Tennis elbow is a painful condition that afflicts...Ch. 8 - Prob. 85PCh. 8 - Prob. 86PCh. 8 - Prob. 87PCh. 8 - Prob. 88PCh. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - A study compared mean electroretinogram (ERG)...Ch. 8 - Prob. 94PCh. 8 - Prob. 95PCh. 8 - Prob. 96PCh. 8 - Prob. 98PCh. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study was performed to determine the effect of...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - A study is being planned to assess whether a...Ch. 8 - Prob. 105PCh. 8 - Prob. 106PCh. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Left ventricular mass (LVM) is an important risk...Ch. 8 - Prob. 109PCh. 8 - Prob. 110PCh. 8 - Prob. 111PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - Prob. 113PCh. 8 - A study sought to demonstrate that soy beans...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - study was recently reported comparing the effects...Ch. 8 - The Diabetes Prevention Study was a randomized...Ch. 8 - Prob. 122PCh. 8 - Prob. 123PCh. 8 - Prob. 124PCh. 8 - Prob. 125PCh. 8 - Prob. 126PCh. 8 - Prob. 127PCh. 8 - A study looked at the influence of retirement on...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Cigarette smoking has important health...Ch. 8 - Prob. 134PCh. 8 - Prob. 135PCh. 8 - Prob. 136PCh. 8 - Prob. 137PCh. 8 - Prob. 138PCh. 8 - Prob. 142PCh. 8 - Prob. 143PCh. 8 - Prob. 144PCh. 8 - Prob. 145PCh. 8 - A study of genetic factors related to coronary...Ch. 8 - A study of genetic factors related to coronary...Ch. 8 - A study of genetic factors related to coronary...Ch. 8 - Prob. 149PCh. 8 - Prob. 150PCh. 8 - Prob. 151PCh. 8 - Prob. 152PCh. 8 - Prob. 153PCh. 8 - Prob. 154PCh. 8 - Prob. 155PCh. 8 - An individual has been exercising at a local gym...Ch. 8 - Prob. 157PCh. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - Suppose we have two groups with sample sizes of 8...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - In a 5-year follow-up of bilateral stimulation of...Ch. 8 - The following data are from a study on Botox...Ch. 8 - The following data are from a study on Botox...Ch. 8 - Prob. 166PCh. 8 - Prob. 167PCh. 8 - Prob. 168PCh. 8 - The EPIC-Norfolk study, a study of diet and cancer...Ch. 8 - Prob. 170PCh. 8 - Prob. 171PCh. 8 - Prob. 172PCh. 8 - Prob. 173PCh. 8 - Prob. 174PCh. 8 - Prob. 175PCh. 8 - Prob. 176P
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