Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Textbook Question
Chapter 8, Problem 41P
The degree of clinical agreement among physicians on the presence or absence of generalized lymphadenopathy was assessed in 32 randomly selected participants from a prospective study of male sexual contacts of men with acquired immunodeficiency syndrome (AIDS) or an AIDS-related condition (ARC) [8]. The total number of palpable lymph nodes was assessed by each of three physicians. Results from two of the three physicians are presented in Table 8.15.
Perform the test in Problem 8.40, and report a p-value
Table 8.15 Reproducibility of assessment of number of palpable lymph nodes among sexual contacts of AIDS or ARC patients
8.40 Should a one-sided or a two-sided test be performed? Why?
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A new drug for pain relief is being tested within a given palliative care population. The new drug is being compared to an already approved pain relief drug that is commonly used in providing palliative care to patients who experience chronic severe pain. Assume the patients are asked to rate the pain on a scale from 1 to 10, and the data presented below was obtained from a small study designed to compare the effectiveness of the two drugs. Set up and interpret the results of a Mann-Whitney U test with an alpha of .05.
Pain Rating as Reported by Patients
Old Drug 1 2 2 4 6
New Drug 1 2 2 3 7
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New Drug
Old Drug
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A new drug for pain relief is being tested within a given palliative care population. The new drug is being compared to an already approved pain relief drug that is commonly used in providing palliative care to patients who experience chronic severe pain. Assume the patients are asked to rate the pain on a scale from 1 to 10, and the data presented below was obtained from a small study designed to compare the effectiveness of the two drugs. Set up and interpret the results of a Mann-Whitney U test with an alpha of .05.
Pain Rating as Reported by Patients
Old Drug 1 3 3 4 6
New Drug 1 2 3 3 7
Chapter 8 Solutions
Fundamentals of Biostatistics
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