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A possible important environmental determinant of lung
Assuming this is regarded as a pilot study, how many children are needed in each group (assuming equal numbers in each group) to have a 95% chance of detecting a significant difference using a two-sided test with α = .05?
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Fundamentals of Biostatistics
- A possible important environmental determinant of lung function in children is the amount of cigarette smoking in the home. Suppose this question is studied by selecting two groups: Group 1 consists of 23 nonsmoking children 5−9 years of age, both of whose parents smoke, who have a mean forced expiratory volume (FEV) of 2.1 L and a standard deviation of 0.7 L; group 2 consists of 20 nonsmoking children of comparable age, neither of whose parents smoke, who have a mean FEV of 2.3 L and a standard deviation of 0.4 L. A) Assuming this is regarded as a pilot study, how many children are needed in each group (assuming equal numbers in each group) to have a 95% chance of detecting a significant difference using a two-sided test with α = .05? B) Answer the question in Problem A if the investigators use a one-sided rather than a two-sided test. Suppose 40 children, both of whose parents smoke, and 50 children, neither of whose parents smoke, are recruited for the study. C) How much power would…arrow_forwardA possible important environmental determinant of lung function in children is the amount of cigarette smoking in the home. Suppose this question is studied by selecting two groups: Group 1 consists of 23 nonsmoking children 5−9 years of age, both of whose parents smoke, who have a mean forced expiratory volume (FEV) of 2.1 L and a standard deviation of 0.7 L; group 2 consists of 20 nonsmoking children of comparable age, neither of whose parents smoke, who have a mean FEV of 2.3 L and a standard deviation of 0.4 L. Suppose 40 children, both of whose parents smoke, and50 children, neither of whose parents smoke, are recruitedfor the study.*8.37 How much power would such a study have using atwo-sided test with significance level = .05, assuming thatthe estimates of the population parameters in the pilot studyare correct?*8.38 Answer Problem 8.37 assuming a one-sided ratherthan a two-sided test is used.arrow_forwardNote- bolded quiz have already answered A possible important environmental determinant of lung function in children is the amount of cigarette smoking in the home. Suppose this question is studied by selecting two groups: Group 1 consists of 23 nonsmoking children 5-9 years of age, both of whose parents smoke, who have a mean forced expiratory volume (FEV) of 2.1 L and a standard deviation of 0.7 L; group 2 consists of 20 nonsmoking children of comparable age, neither of whose parents smoke, who have a mean FEV of 2.3 L and a standard deviation of 0.4 L.*8.31 What are the appropriate null and alternative hypotheses to compare the means of the two groups? *8.32 What is the appropriate test procedure for the hypotheses in Problem 8.31? *8.33 Carry out the test in Problem 8.32 using the criticalvalue method. *8.34 Provide a 95% CI for the true mean difference in FEV between 5- to 9-year-old children whose parents smoke and comparable children whose parents do not smoke. *8.35 Assuming…arrow_forward
- A dietitian wishes to see if a person’s cholesterol level will be changed if the diet is supplemented by a certain mineral. Four subjects were pre-tested, and they took the mineral supplement for a 6-week period. The results are shown in the table. Is there sufficient evidence to conclude that the population mean of cholesterol levels has been changed after six weeks at α=0.2α=0.2? Assume that the differences are from an approximately normally distributed population. Subject Cholestrol Level (mg/dl) Cholestrol Level after 6 Weeks (mg/dl) dd ¯dd¯ (d−¯d)2(d-d¯)2 1 206 217 11 2 219 184 -35 3 202 204 2 4 213 205 -8 Total -30 a) Calculate the mean, the sum of the squared deviation from the mean, and the standard deviation of differences. Do not include the unit for each answer: ¯d=d¯= (do not round) ∑(d−¯d)2=∑(d-d¯)2= (do not round) sd=sd= (rounded to one decimal place) b) Perform the hypothesis test in the following steps: Step 1.…arrow_forwardWhich of the following is NOT CORRECT? A) The past purchase frequency (freqi) affects the purchase probability positively – i.e., customers with high past purchase frequency are more likely to purchase our product in the next year than those with low past purchase frequency. B) In general, customers are likely to buy our product because the baseline parameter is negative. C) High-income customers are more likely to purchase our product in the next year than low- income customers because the coefficient corresponding to the income variable (incomei) is positive. D) Although the number of flyers (nmaili) positively affects the purchase probability, it is not guaranteed that sending flyers to customers as many as possible maximizes profits.arrow_forwardA researcher has developed a new drug designed to reduce blood pressure. In an experiment, 22 subjects were assigned randomly to the treatment group and received the new experimental drug. The other 24 subjects were assigned to the control group and received a standard, well-known treatment. After a suitable period, the reduction in blood pressure for each subject was recorded. A summary of these data is: nn x¯x¯ ss Treatment group (new drug) 22 23.48 8.01 Control group (old drug) 24 18.52 7.15 Without using software, how would you estimate the number of degrees of freedom for this problem? Select one: use the larger value, 23, chosen from the two options 21 and 23 use the smaller value, 22, chosen from the two options 22 and 24 use the larger value, 24, chosen from the two options 22 and 24 use the smaller value, 21, chosen from the two options 21 and 23arrow_forward
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- Assume that as a portfolio manager the beta of your portfolio is 1.15 and that your performance is exactly on target with the SML data under condition 1. If the true SML data is given by condition 2, how much does your performance differ from the true SML? (1) RFR = 0.0625 Rm(proxy) = 0.12 (2) RK = 0.078 Rm(true) = 0.10arrow_forwardSuppose that the index model for two Canadian stocks HD and ML is estimated with the following results: RHD =-0.03+2.10RM+eHD R-squared =0.7 RML =0.06+1.60RM+eML R-squared =0.6 σM =0.15 where M is S&P/TSX Comp Index and RX is the excess return of stock X. What is the covariance and the correlation coefficient between HD and ML?arrow_forward
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