Chapter 8, Problem 34P

Arrange the following list of eukaryotic gene elements in the order in which they would appear in the genome and in the direction traveled by RNA polymerase along the gene. Assume the gene’s single intron interrupts the open reading frame. Note that some of these names are abbreviated and thus do not distinguish between elements in DNA versus RNA. For example, splice-donor site is an abbreviation for DNA sequences transcribed into the splice-donor site because splicing takes place on the gene’s RNA transcript, not on the gene itself. Geneticists often use this kind of shorthand for simplicity, even though it is imprecise. (a) splice-donor site; (b)3′ UTR; (c) promoter; (d) stop codon; (e) nucleotide to which methylated cap is added; (f) initiation codon; (g) transcription terminator; (h) splice-acceptor site; (i) 5′ UTR; (j) poly-A addition site; (k) splice branch site.