Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 16, Problem 48SA
Summary Introduction

To review:

The function of PYY (peptide YY) and the location of synthesis of PYY.

Introduction:

Peptides are described as the short chains of amino acids joined together by amide or peptide bonds. A peptide bond is classified as a covalent bond formed by the reaction of the amino group of one amino acid residue and the carboxyl group of another amino acid residue.

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Name three biologically active peptides. Mention their functions.
Peptide YY (PYY) is a 36-amino acid peptide that is so named because it contains twobiochemically relevant tyrosine residues.Describe the function of PYY and state where it is synthesized.
H CH₂ H₂C HC-CH3 CH₂ H H₂C (S) H₂C H CH₂ CH₂ CH₂ NH O C NH NH₂ a) Which of the following statements about this peptide are correct? Group of answer choices Treatment of this peptide with trypsin generates two products. This peptide is a substrate for carboxypeptidase A Treatment of this peptide with cyanogen bromide generates a pentapeptide and a tripeptide. Treatment of this peptide with chymotrypsin generates three products. Treatment of this peptide with elastase generates 2 products. None of the above statements are correct. b) What is the sequence of this peptide using one letter abbreviations? c) What is the pH which would correspond to the ionization of the peptide as drawn above? 1, 5, 7, 10, 14

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Biochemistry: The Molecular Basis of Life

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