Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 16, Problem 9RQ
Summary Introduction

To review:

Definition of the following terminologies:

a. Tumor promoter

b. Guanine nucleotide exchange factor

c. DAG

d. Steady state

e. IP3

Introduction:

In almost all the organisms, the central metabolic pathways are similar. A precise balance is maintained between the catabolic and anabolic processes. The growth of cells and differentiation are controlled by several factors. In case, if regulation becomes impaired, then body suffers damage such as tumor.

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Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) are important biological macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA reproduction. c) Describe an example of biomedical application that utilizes a protein folding technique. d) Describe the effect of pH on the oxygen binding affinity of hemoglobin.
QUESTION 8 Consider the pathway for the synthesis of the amino acid arginine in Neurospora: ARG-E → citrulline ARG-F ARG-H ornithine argininosuccinate arginine Mutant strains of Neurospora may carry one or more mutations. Neurospora mutant strain b is grown on minimal media plus supplements as shown. Growth is shown by (+) and no growth is shown by (o). Supplements ornithine mutant nothing citrulline arginino- succinate arginine strain What can you conclude from these data? O Strain a has only one mutation and it is in ARG-E. O Strain b has only one mutation and it is in ARG-H. O Strain a has a mutation in ARG-F and strain b has a mutation in ARG-E. O Strain b has mutations in ARG-E, ARG-F, and ARG-H. + +
. ___________________________ factors are proteins thatregulate or initiate RNA synthesis by binding directly orindirectly to specific DNA sequences called responseelements.

Chapter 16 Solutions

Biochemistry: The Molecular Basis of Life

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