Concept explainers
List and briefly describe four types of molecules that can bind to an ncRNA.
To review:
Molecules that can bind to ncRNA (non-coding RNA)
Introduction:
The ncRNA stands for non- coding RNAs and has the ability to carry out various functions and affect processes like gene expression and translation of messenger RNA. The functions include acting as a scaffold, guide, alteration of protein structure, ribozyme, blocker, and decoy.
Explanation of Solution
ncRNA controls certain functions due to its proximity and binding ability to certain important molecules like DNA (Deoxyribonucleic acid), RNA (Ribonucleic acid), proteins and small molecules. This binding is facilitated by multiple binding sites and complementary base pairing.
1. DNA: binding of ncRNAs to DNA is due to its strong affinity to DNA molecules due to complementary base pairing.
2. RNA: binding of ncRNAs is due to complementary base pairing of ncRNAs and messenger RNA molecules.
3. Proteins and small molecules:ncRNAs bind to proteins and other small molecules due to multiple binding sites and affect processes like transcription and translation.
The figure given below shows the binding of ncRNA to different molecules of DNA, RNA, proteins, and small molecules:
Therefore, it can be concluded that ncRNAs bind to different molecules like DNA, RNA, proteins and small molecules due to complementary base pairing and multiple binding sites on ncRNA molecule.
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Chapter 17 Solutions
Genetics: Analysis and Principles
- An ncRNA may have the following functions: scaffold, guide, alterer of protein function or stability, ribozyme, blocker, and/or decoy. Which of these functions are mediated by each type of ncRNA listed next? Note: A singlencRNA may have more than one function. A. tRNAB. rRNAC. SRP RNAD. piRNAarrow_forwardExplain how ncRNA uses complementary base pairing with RNA to affect gene expression.arrow_forwardIs the PAM sequence required for Cas9-mediated cleavage of a single-stranded strand of DNA (when that strand is complementary to the crRNA)? Explain.arrow_forward
- How is the sgRNA different from certain components of the bacterial defense system described?arrow_forwardDescribe several different functions of the RNA component of snRNPsarrow_forwardAn ncRNA may have the following functions: scaffold, guide,alterer of protein function or stability, ribozyme, blocker, and/ordecoy. Which of those functions is/are mediated by each of thencRNAs listed next? (Note: A single ncRNA may have more thanone function.) A. HOTAIRB. RNA of RNasePC. microRNAD. crRNAarrow_forward
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