Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 17.6, Problem 2COMQ
Let's suppose that the overexpression of a particular miRNA was associated with pancreatic cancer. Which of the following agents might be effective in treating this type of cancer?
a. Enoxacin
b. A DNA demethylating agent
c. An anti-miRNA oligonucleotide
d. Both a and b
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Chapter 17 Solutions
Genetics: Analysis and Principles
Ch. 17.1 - Which of the following can bind to ncRNAs? a. DNA...Ch. 17.1 - 2. When an ncRNA functions as a decoy, it
a....Ch. 17.1 - Prob. 3COMQCh. 17.2 - 1. Which of the following functions does HOTAIR...Ch. 17.3 - 1. The process of RNA interference may lead to
a....Ch. 17.3 - 2. In catalyzing the methylation or...Ch. 17.4 - 1. Which of the following is a function of SRP?...Ch. 17.5 - 1. Which of the following components are needed...Ch. 17.5 - 2. In the CRISPR-Cas system, what does the...Ch. 17.5 - Which of the following is a function of the...
Ch. 17.6 - Prob. 1COMQCh. 17.6 - Let's suppose that the overexpression of a...Ch. 17 - 1. List and briefly describe four types of...Ch. 17 - 2. An ncRNA may have the following functions:...Ch. 17 - 3. What is meant by the term RNA world? Describe...Ch. 17 - Explain how HOTAIR plays a role in the...Ch. 17 - What is the phenomenon of RNA interference (RNAi)?...Ch. 17 - With regard to RNAi, what are three possible...Ch. 17 - 7. What is the difference between an miRNA and an...Ch. 17 - Together with a specific set of proteins, snoRNAs...Ch. 17 - Describe the structure of SRP in eukaryotes, and...Ch. 17 - Look at Figure 17.6 and predict what would happen...Ch. 17 - Compare and contrast the roles of crRNA and...Ch. 17 - In the CRISPR-Cas system, does the tracrRNA act as...Ch. 17 - Prob. 13CONQCh. 17 - Outline the steps that occur when piRISCs silence...Ch. 17 - List five types of cancer in which ncRNAs can be...Ch. 17 - Prob. 16CONQCh. 17 - A protein called trypsin, which plays a role in...Ch. 17 - Prob. 2EQCh. 17 - Prob. 3EQCh. 17 - As described in Chapter 21, the CRISPR-Cas system...Ch. 17 - Prob. 5EQCh. 17 - Prob. 6EQCh. 17 - Prob. 1QSDCCh. 17 - Go to the PubMed website and do a search using the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What strategy does a genetically encoded calcium indicator look like to allow fluorescence imaging of only one cell type in an acute slice of the brain? A.The use of fluorescent protein expression inhibitors in other cells B.The injection of a recombinant virus causing the death of other cells C.The use of a promoter specific to these cells D.Activation of membrane receptors specific to these cellsarrow_forwardmiRNA molecules act as specificity factors, which direct effector proteins to target ______ molecules via base-pairing. A. RNA B. Carbohydrate C. Lipid D. DNA E. Proteinarrow_forwardWhich sequence is most likely to be found in a promoter? a) CGGTGTATATCGTAC b) GTACAGTCATCCCGT c) AAATCTACTACGATT d) GGGTTGGGTTGGGTTarrow_forward
- Compare and contrast the origins and functions of miRNA and siRNAarrow_forwardCompare and contrast anti-miRNA oligonucleotides, locked nucleicacids (LNAs), and antagomirs, which may eventually be used to treat certain forms of cancer.arrow_forwardAfter tmRNA releases an mRNA and aberrant polypeptide from a stuck ribosome, the resulting polypeptide will A) be translated B) be destroyed by a protease C) be inserted into the cell membrane D) be used to regulate gene expressionarrow_forward
- In RNA silencing, siRNAs and miRNAs usually bind to which part of the mRNA molecules that they control? a. 5′ UTR b. Coding region c. 3′ poly(A) tail d. 3′ UTRarrow_forwarda mutation in the gene encoding Dicer would most likely result in: A) a failure to break the H bonds holding the 2 strands of the siRNA together B) the inability to form H bonds betwen the siRNA and the complementary mRNA that it targets. C) the inability of the target mRNA to be cleaved upon H bonding with the siRNA D) a failure to produce siRNAs responsible for knocking down gene expression E) the failure to produce a dsRNA specific to your gene of interestarrow_forwardGene expression in bacteria is controlled by the operon model. a) Why is the operon model important? b) Why is the trp operon known as a repressible operon?arrow_forward
- What is the main difference between Sirna and miRNA?arrow_forward. Which of the following is an example of post-transcriptional gene repression?a. The amount of RNA transcribed from a gene isreduced because the DNA is methylated.b. The amount of RNA is reduced because it is rapidlydegraded.c. The amount of protein made is reduced by action ofan miRNA.d. b and c are both correct.arrow_forwardBelow is a graphical representation of eukaryotic precursor mRNA. A. Outline each modification that must happen to get a mature m-RNA. B. How does the absence of introns in prokaryotic genes affect prokaryotic gene expression? C. How will gene expression be affected if all of the spliceosomes are removed from the bacteria sample? Explain.arrow_forward
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