Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 17.4, Problem 1COMQ
Which of the following is a function of SRP?
a. Pausing translation of polypeptides with an ER signal sequence
b. Binding to an SRP receptor in the ER membrane
c. Docking the ribosome over a channel
d. All of the above
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Which of the following is the function of transfer RNA?
a.Makes up the structure of ribosomes
b.Stores genetic information
c.Carries the message that guides polypeptide assembly
d.Delivers amino acids to ribosomes
Which of the following is true of ribosome rescue? (C & E wrong)
A. The process produces a protein that is tagged for degradation.
B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide.
C. A partially translated mRNA becomes fully degraded before it can be translated further.
D. No protein is produced in the process.
E. Stalled ribosomes are released in the absence of a stop codon.
The...... attached to the ER signal sequence of the newly synthesized protein and ribosome attch to the ....... on the ER to direct the entry of the newly synthesized protein in the ER.
a) t snare.....v snare.
b) Rab.....tethering.
c) SRP.....SRP.
d) Clathrin..... Adaptin
Chapter 17 Solutions
Genetics: Analysis and Principles
Ch. 17.1 - Which of the following can bind to ncRNAs? a. DNA...Ch. 17.1 - 2. When an ncRNA functions as a decoy, it
a....Ch. 17.1 - Prob. 3COMQCh. 17.2 - 1. Which of the following functions does HOTAIR...Ch. 17.3 - 1. The process of RNA interference may lead to
a....Ch. 17.3 - 2. In catalyzing the methylation or...Ch. 17.4 - 1. Which of the following is a function of SRP?...Ch. 17.5 - 1. Which of the following components are needed...Ch. 17.5 - 2. In the CRISPR-Cas system, what does the...Ch. 17.5 - Which of the following is a function of the...
Ch. 17.6 - Prob. 1COMQCh. 17.6 - Let's suppose that the overexpression of a...Ch. 17 - 1. List and briefly describe four types of...Ch. 17 - 2. An ncRNA may have the following functions:...Ch. 17 - 3. What is meant by the term RNA world? Describe...Ch. 17 - Explain how HOTAIR plays a role in the...Ch. 17 - What is the phenomenon of RNA interference (RNAi)?...Ch. 17 - With regard to RNAi, what are three possible...Ch. 17 - 7. What is the difference between an miRNA and an...Ch. 17 - Together with a specific set of proteins, snoRNAs...Ch. 17 - Describe the structure of SRP in eukaryotes, and...Ch. 17 - Look at Figure 17.6 and predict what would happen...Ch. 17 - Compare and contrast the roles of crRNA and...Ch. 17 - In the CRISPR-Cas system, does the tracrRNA act as...Ch. 17 - Prob. 13CONQCh. 17 - Outline the steps that occur when piRISCs silence...Ch. 17 - List five types of cancer in which ncRNAs can be...Ch. 17 - Prob. 16CONQCh. 17 - A protein called trypsin, which plays a role in...Ch. 17 - Prob. 2EQCh. 17 - Prob. 3EQCh. 17 - As described in Chapter 21, the CRISPR-Cas system...Ch. 17 - Prob. 5EQCh. 17 - Prob. 6EQCh. 17 - Prob. 1QSDCCh. 17 - Go to the PubMed website and do a search using the...
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- Which of the following is a function of SRP?a. Pausing translation of polypeptides with an ER signalsequenceb. Binding to an SRP receptor in the ER membranec. Docking the ribosome over a channeld. All of the abovearrow_forwardAfter ingesting a bacteria, macrophages process bacterial parts and ‘present’ them to acquired immunity cells so the acquired immune cells recognize these invaders again in the future. The antigen-presenting proteins ultimately end up in the plasma membrane. Where did it receive the post-translation modification that determined its final location? a. The ribosome b. The ER c. The Golgi d. The vesiclearrow_forwardWhich of the following is most likely to have a small protein called ubiquitin attached to it? A. a cell surface protein that requires transport from the ER B. a regulatory protein that requires sugar residues to be attached -C. an mRNA that is leaving the nucleus to be translated D. a protein that has lost a disulphide bond stabilizing its 3-dimensional structure, causing it to misfoldarrow_forward
- A rare mutation can result in eukaryotic cells that causes a failure in the cell to synthesize the Signal Recognition Particle (SRP). Failure to make the SRP would impact protein synthesis by ________ . A. Preventing transition of bound ribosomes to free ribosomes B. Preventing binding of ribosomes to the rough ER during synthesis of proteins with a signal sequence C. Preventing export of mRNA out of the nuclear envelope D. Preventing binding of ribosomes to the smooth ER during synthesis of proteins with a signal sequencearrow_forwardWhich of the following most likely has a sequence of hydrophobic amino acids that permits the protein to be embedded in membranes? Select one: a. translocator (TIM/TOM) b. none of the above c. signal peptidase d. chaperone (HSP) e. ubiquitinarrow_forwardThe ribosome is needed for translation of mRNA (a) because it has the enzyme for adding amino acids to the 5’ end of a tRNA (b) because the ribosomal RNA contains the codon which determines the sequence of amino acids in a protein (c) because it positions tRNA and mRNA so that correct pairing of codon and anti-codon can occur (d) because it has an enzyme that removes introns from mRNA (e) all of the abovearrow_forward
- The ribosome is needed for translation of mRNA (a) because it has the enzyme that forms peptide bonds between amino acids (b) because the ribosomal RNA contains the codon which determine the sequence of amino acids in a protein (c) because it contains the enzyme that links the amino acids and tRNA (d) because it has enzyme that removes introns from mRNA (e) all of the abovearrow_forwardThe “A” site in the ribosome refers to the: A. binding site for charged t-RNA molecules during protein synthesis B. Site that allows for tRNAs to exit C. a site that holds the tRNA which is linked to the growing polypeptide chain D. none of these answeresarrow_forwardWhen would a ribosome bind to a promoter sequence? A) It wouldn't. A promoter is a DNA sequence, and ribosomes don't bind to DNA. B) When the ribosome needs to transcribe the gene that that promoter controls. C) When the ribosome is translating the DNA sequence of a gene. D) When there is a start codon (AUG) in the promoter sequence. .arrow_forward
- Which of the following statements is representative of transduction? A) Binding of ligand to cell surface receptor B) Gene expression C) activation of relay molecules D) Spread of diffusion throughout a cellarrow_forwardTo facilitate movement of mRNA from the nucleus into the cytoplasm, what is added to the 3’ end of mRNA? a) Ribosomes b)Transcription factors c) A cap of modified nucleotides d) Modified tRNA molecules e) A Poly-a-tailarrow_forwardWhich of the following is an example of a transcription factor? A) gene B) a repressor C) a ribosome D) an intronarrow_forward
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