Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 17, Problem 4CONQ
Explain how HOTAIR plays a role in the transcriptional regulation of particular genes.
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Explain how iRNA works to down-regulate gene expression.
Explain how the ncRNA known as HOTAIR plays a role in gene repression.
If the binding activity was purified, suggest two experimental approaches that could be taken to verify that this factor is in fact a transcription factor? Explain.
Chapter 17 Solutions
Genetics: Analysis and Principles
Ch. 17.1 - Which of the following can bind to ncRNAs? a. DNA...Ch. 17.1 - 2. When an ncRNA functions as a decoy, it
a....Ch. 17.1 - Prob. 3COMQCh. 17.2 - 1. Which of the following functions does HOTAIR...Ch. 17.3 - 1. The process of RNA interference may lead to
a....Ch. 17.3 - 2. In catalyzing the methylation or...Ch. 17.4 - 1. Which of the following is a function of SRP?...Ch. 17.5 - 1. Which of the following components are needed...Ch. 17.5 - 2. In the CRISPR-Cas system, what does the...Ch. 17.5 - Which of the following is a function of the...
Ch. 17.6 - Prob. 1COMQCh. 17.6 - Let's suppose that the overexpression of a...Ch. 17 - 1. List and briefly describe four types of...Ch. 17 - 2. An ncRNA may have the following functions:...Ch. 17 - 3. What is meant by the term RNA world? Describe...Ch. 17 - Explain how HOTAIR plays a role in the...Ch. 17 - What is the phenomenon of RNA interference (RNAi)?...Ch. 17 - With regard to RNAi, what are three possible...Ch. 17 - 7. What is the difference between an miRNA and an...Ch. 17 - Together with a specific set of proteins, snoRNAs...Ch. 17 - Describe the structure of SRP in eukaryotes, and...Ch. 17 - Look at Figure 17.6 and predict what would happen...Ch. 17 - Compare and contrast the roles of crRNA and...Ch. 17 - In the CRISPR-Cas system, does the tracrRNA act as...Ch. 17 - Prob. 13CONQCh. 17 - Outline the steps that occur when piRISCs silence...Ch. 17 - List five types of cancer in which ncRNAs can be...Ch. 17 - Prob. 16CONQCh. 17 - A protein called trypsin, which plays a role in...Ch. 17 - Prob. 2EQCh. 17 - Prob. 3EQCh. 17 - As described in Chapter 21, the CRISPR-Cas system...Ch. 17 - Prob. 5EQCh. 17 - Prob. 6EQCh. 17 - Prob. 1QSDCCh. 17 - Go to the PubMed website and do a search using the...
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- Explain how repressor proteins can be central to theregulation of both catabolic and anabolic operonsarrow_forwardPlease describe the regulatory role of enhancers that binds to responsible regulators to activate the target gene at a given time and place through comparing different organisms according to the presence of regulatory sequencesarrow_forwardHow were bacterial promoters first identified? Discuss their placement within the gene and roles in transcription initiation. Further discuss how the holoenzyme engages a promoter.arrow_forward
- Explain why inactivation of the O1 sequence of the lac operator almost completely abolishes repression of the lac operon.arrow_forwardMATCH THE FF. WITH THE CHOICES BELOW TATA sequence CAAT nucleotide within core promoter 3 enhancers silencers heat shock element (HSE) the glucocorticoid response element (GRE) the metal response element (MRE) CHOICES -Response elements (REs) -Core promoter elements -Regulatory elementsarrow_forwardExplain how the lac operon is both positively and negativelycontrolled.arrow_forward
- Explain how the Pyrococcus furiosus TrmBL1 transcriptionregulator is able to act as both an activator and a repressor.arrow_forwardNoncoding ribonucleic acid (RNA) interference/regulation in reguards to gene expression. Provide examples.arrow_forwardExplain the features of the Initiator (Inr) elements, BREs, DPEs, and MTEs of focused promoters.arrow_forward
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