Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 6, Problem 64TQ
Summary Introduction

To review:

The inhibition of alcohol dehydrogenase by 4-methylpyrazole at variousconcentrations as shown in Lineweaver–Burk plot.

Introduction:

The Lineweaver–Burk plot shows the value for Michaelis–Menten constant and maximum velocity by measuring the initial reaction velocities at various substrate concentration. The 4-methylpyrazole is a potent inhibitor of alcohol dehydrogenase in ethanol glycol poisoning. It binds with the active site of the enzyme and blocks the site for the substrate.

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Biochemistry: The Molecular Basis of Life

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