Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 17, Problem 27RQ
Summary Introduction
To review:
The process of retention of DNA (deoxyribonucleic acid) methylation from one generation to another.
Introduction:
The DNA of an individual carries the genomic information. DNA methylation is the process of addition of a methyl group to the carbon-5 of the cytosine (C) residue. The process of the DNA methylation is essential for normal development. It plays a major role in various molecular biology processes, like repression of transposable elements, X-chromosome inactivation, genomic imprinting, aging, and carcinogenesis.
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QUESTION 24
During lagging strand synthesis of DNA, Okazaki fragments are linked together by ___________.
DNA polymerase I
Primase
Beta clamps
DNA Ligase
QUESTION NO. 1 Base excision repair
A. is used only for bases that have been deaminated.
B. uses enzymes called DNA glycosylases to generate an abasic sugar site.
C. removes about 10 to 15 nucleotides.
D. does not require an endonuclease.
E. recognizes a bulky lesion.
QUESTION NO. 2
Termination of a prokaryotic transcriptA. is a random process.
B. requires the presence of the rho subunit of the holoenzyme.
C. does not require rho factor if the end of the gene contains a G-C rich palindrome.
D. is most efficient if there is an A-T-rich segment at the end of the gene.
E. requires an ATPase in addition to rho factor.
QUESTION NO. 3
Eukaryotic transcription
A. is independent of the presence of upstream consensus sequences.
B. may involve a promoter located within the region transcribed rather than upstream.
C. requires a separate promoter region for each of the three ribosomal RNAs transcribed.
D. requires that…
QUESTION 25
During lagging strand synthesis of DNA, the RNA primers are replaced with DNA by __________.
DNA Polymerase I
DNA Polymerase II
DNA Polymerase III
Primase
Chapter 17 Solutions
Biochemistry: The Molecular Basis of Life
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