Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 17, Problem 60TQ
Summary Introduction

To review:

The frequent pairing of 5-bromouracil (analog of thymine) with guanine.

Introduction:

There is always a complementary base pairing between the purine and pyrimidine in DNA double helix. The base adenine (A) forms two hydrogen bonds with thymine (T) whereas guanine (G) forms three hydrogen bonds with cytosine (C). The structure of DNA can be damaged by certain xenobiotics, which include base analogs, alkylating agents as well as intercalating agents.

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Biochemistry: The Molecular Basis of Life

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