Concept explainers
Interpretation:
The relationship between pyruvate concentration and
Concept introduction:
Ketone bodies are water soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- How many moles of Acetyl CoA are produced from the beta oxidation of Lauric Acid?arrow_forwardWhy does a deficiency of carbohydrates in the diet lead to ketone body formation?arrow_forwardWhich steps of glycolysis are irreversible? What bearing does this observation have on the reactions in which gluconeogenesis differs from glycolysis?arrow_forward
- How many moles of acetyl-CoA are produced by the complete catabolism of 1 mol of sucrose?arrow_forwardIf a fatty acid containing 13 carbons is subjected to Beta oxidation, how many molecules of Acetyl CoA can be produced?arrow_forwardHow many acetyl CoA molecules can be produced during the complete β-oxidation of this fatty acid?arrow_forward
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- Consider the reactions of ketogenesis. (a) What role does acetyl-CoA play?(b) How many acetyl-CoA molecules are used in the production of the ketonebodies?(c) What is the essential role of ketone bodies during prolonged starvation?arrow_forwardHow many NADH and FADH2 will be produced when this fatty acid is completely metabolized?arrow_forwardWhy would glutamate utilize the oxidative deamination pathway over transamination – especially if removal of NH4+ requires ATP? Would it not be favorable for the body to just use transamination?arrow_forward
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