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Concept explainers
Interpretation:
The fate not possible for fatty acid-generated acetyl CoA has to be identified.
Concept introduction:
Fatty acids are molecules that are long hydrocarbon chain of
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as a β-oxidation pathway. Acetyl CoA, FADH2, and NADH are produced in this reaction.
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- Which of the following is incorrect about the conversion of acetyl-CoA (2 C) to malonyl- COA (3 C)? O a. It is irreversible O b. O c. It is a decarboxylation It is regulated Od. It is the first step of fatty acid synthesis +arrow_forwardWhich of the following statements is/are TRUE about the PPP? A. Most active in cells where lipids are synthesized. B. Reactions involved are oxidative and non-oxidative. C. Also called the hexose monophosphate shunt pathway. D. Occurs in the cytosol.arrow_forwardBefore a fatty acid can undergo β-oxidation, it must be activated and then shuttled across the inner mitochondrial membrane. The activating agent and shuttle molecule are, respectively: A. CoA and carnitine B. CoA and citrate C. acetyl CoA and carnitine D. acetyl CoA and citratearrow_forward
- In the context of fatty acid oxidation to acetyl CoA, indicate whether each of the following substances is involved in (1) fatty acid activation, (2) fatty acid trans-port, or (3) b-oxidation pathway. More than one choice may be correct in a given situation. a. AMp b. FAD c. Acyl CoA d. H2Oarrow_forwardWhich of the following statements is true of the β - oxidation of an unsaturated fatty acid? a. It is identical to the β-oxidation of a saturated fatty acid. b. It involves an extra step to convert a cis double bond to a trans double bond. c. It involves an extra step to convert a trans double bond to a cis double bond. d. It is completely different from the β-oxidation of a saturated fatty acid.arrow_forwardOrder the steps that results in a triacylglycerol containing two palmitic acids and one stearic acid. a. Diacylglycerol reacts with an fatty-acyl-CoA b. Phosphate is remove from phosphatidic acid to form diacylglycerol c. Two of the fatty acyl-CoAs react with glycerol-3-phosphate d. An elongase produce stearic acid e. Stearoyl-CoA is synthesized…arrow_forward
- Differentiate fatty acid synthesis and degradation in terms of the following: Fatty acid synthesis Fatty acid degradation a. Subcellular location b. End product c. Co-factors d. Carriers of acyl/acetyl groups between the mitochondria and the cytosolarrow_forwardWhich of the following is NOT produced during the reactions of acetyl-CoA formation? (only one choice is correct) A. Acetyl CoA B. Electrons C. CO2 D. ATParrow_forwardA patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor Barrow_forward
- Which one of the following statements concerning gluconeogenesis is correct? a. It is inhibited by elevated levels of acetyl CoA. b. It occurs in muscle. c. It is important in maintaining blood glucose during normal overnight fast. d. It is stimulated by fructose 2,6-bisphosphate.arrow_forwardFatty acid biosynthesis differs from β-oxidation in that: A. NADP+ is used in biosynthesis but not in β-oxidation. B. Biosynthesis uses malonyl-CoA while β-oxidation does not. C. Biosynthesis occurs in the cytoplasm while β-oxidation occurs in the mitochondria. D. Biosynthesis is a reductive process while β-oxidation is oxidation.arrow_forwardWhich of the following statements concerning gluconeogenesis is NOT true? a. Gluconeogenesis is to make glucose from glycogen. b. Many of the reactions of gluconeogenesis are glycolytic reactions going in reverse. c. The process of gluconeogenesis consumes ATP. d. The process of gluconeogenesis is regulated by ATP. e. Gluconeogenesis maintains the blood glucose level long after all dietary glucose has been absorbed and oxidized.arrow_forward
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