Concept explainers
(a)
Interpretation:
The step in which the first hydrogenation reaction occurs in the first cycle of the lipogenesis pathway has to be identified.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.
(b)
Interpretation:
The step in which dehydration reaction occurs in the first cycle of the lipogenesis pathway has to be identified.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.
(c)
Interpretation:
The step in which the production of acetoacetyl ACP occurs in the first cycle of the lipogenesis pathway has to be identified.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.
(d)
Interpretation:
The step in which crotonyl ACP is used as a reactant in the first cycle of the lipogenesis pathway has to be identified.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
A cyclic process occurs in the enzyme fatty acid synthase. One turn of this cyclic process constitutes four reactions. The various intermediates formed in the process are associated with a carrier protein known as ACP.
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EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
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- Define the following terms:a. homoglycanb. heteroglycanc. amylosed. amylopectine. enterocytearrow_forwardWhich of the following statements about the ß-oxidation cycle is/are TRUE?A. The fatty acyl produced is shorter by 2 carbon atoms than the previous cycle.B. The two oxidation reactions involve both NADH and NADPH.C. Acetyl-CoA is produced in the hydration reaction.D. In the cleavage reaction, the bond between the α- and β- carbons become a double bund.arrow_forwardFor each of the following conditions, state whether this condition would be occurring during gluconeogenesis, glycolysis, or both in liver cells. a. Transporting malate from the cytosol into the mitochondria. _____________ b. Transporting pyruvate from the cytosol into the mitochondria. _____________ c. We would have an increased (or increasing) concentration of F26BP. __________ d. Increased concentration of F6P.__________ e. Hexokinase IV (or glucokinase) is found in the nucleus of the cell. __________ f. The enzyme that synthesizes/breaks down F26BP is phosphorylated. __________ g. Elevated levels of glucagon in the blood. ____________arrow_forward
- Adipose triglyceride lipase (ATGL) hydrolyzes a fatty acyl group from: A) monoacylglycerol. B) diacylglycerol. C) triacylglycerol. D) A and C. E) B and C.arrow_forwardFor each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).arrow_forwardLipases break down triacylglycerols by catalyzing hydrolysis. What are the products of this hydrolysis?arrow_forward
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