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Concept explainers
Interpretation:
The correct pair of keto acid intermediates in lipogenesis and the citric acid cycle respectively has to be identified.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. This process is the reverse of the degradation of fatty acid.
The citric acid cycle includes the reactions in which the acetyl part of acetyl CoA is oxidized and leads to the formation of carbon dioxide and CoA-SH. Carbon dioxide produced is exhaled out in the breathing process.
An acid containing both carbonyl and carboxyl
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- For each of the following conditions, state whether this condition would be occurring during gluconeogenesis, glycolysis, or both in liver cells. a. Transporting malate from the cytosol into the mitochondria. _____________ b. Transporting pyruvate from the cytosol into the mitochondria. _____________ c. We would have an increased (or increasing) concentration of F26BP. __________ d. Increased concentration of F6P.__________ e. Hexokinase IV (or glucokinase) is found in the nucleus of the cell. __________ f. The enzyme that synthesizes/breaks down F26BP is phosphorylated. __________ g. Elevated levels of glucagon in the blood. ____________arrow_forwardWhich of the following enzymes is found in gluconeogenesis but not in glycolysis? a. phosphohexose isomerase b. hexokinase c. fructose 1,6-bisphosphatase d. phosphoglycerate kinasearrow_forwardAll of the following classes of enzymes catalyze the Fatty acid synthesis except a. synthetase b. Synthase c. Carboxylase d. Dehydrgenarrow_forward
- Before a fatty acid can undergo β-oxidation, it must be activated and then shuttled across the inner mitochondrial membrane. The activating agent and shuttle molecule are, respectively: A. CoA and carnitine B. CoA and citrate C. acetyl CoA and carnitine D. acetyl CoA and citratearrow_forwardThe rate limiting and committed step of the pentose phosphate pathway is catalyzed by which of the following enzymes? A. Glucose-6-phosphate dehydrogenase B. Hexokinase C. 6-Phosphogluconate dehydrogenase D. Transketolasearrow_forwardCompare and contrast the following items related to lipid metabolism. Cite their main similarities/or differences. 1.lysophosphatidylcholine vs. phosphatidylethanolamine 2.trimyristin vs. triolein. 3. ACP vs. carnitine-acyl transferase.arrow_forward
- Which of the following are the precursors in synthesizing myristic acid? a. 7 malonyl-CoA b. 3 acetyl-CoA, 4 malonyl-CoA c. 1 acetyl-CoA, 6 malonyl-CoA d. 7 acetyl-CoAarrow_forwardIn order to function as a coenzyme, a derivative of pyridoxine (Vit. B6) is necessary. a.transamination b.Deamination by oxidation c. transamination as well as oxidative deamination are involved. d.The urea cycle is the fourth step.arrow_forwardWhich of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenasearrow_forward
- If 14CO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? a. Oxaloacetate b. Citric Acid c. Isocitrate d. Alpha-ketoglutarate e. Succinyl-CoA f .Succinate g. Fumarate h. Malatearrow_forwardCompare and contrast the following items related to lipid metabolism. Cite their main similarities/or differences. 1. Steroid hormones vs. prostaglandins (in terms of their biosynthetic pathways). 2. Fatty acid synthase complex vs. pyruvate dehydrogenase complex.arrow_forwardMatch the coenzymes and/or substrates with their corresponding glycolytic enzymes. Note that an enzyme can match with more than one coenzyme or substrate in the list. ATP NAD+ Dihydroxyacetone phosphate A. Glucose 1-dehydrogenase B. Phosphofructokinase-1 C. Glyceraldehyde 3-phosphate dehydrogenase D. ATPase E. Triose phosphate isomerasearrow_forward
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