Concept explainers
(a)
Interpretation:
Whether the molecule acetoacetyl CoA is a C2, C4, C6 or C8 molecule has to be determined.
Concept introduction:
(b)
Interpretation:
Whether the molecule 3-hydroxy-3-methylglutaryl CoA is a C2, C4, C6 or C8 molecule has to be determined.
Concept introduction:
Ketone bodies are water-soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
(c)
Interpretation:
Whether the molecule acetoacetate is a C2, C4, C6 or C8 molecule has to be determined.
Concept introduction:
Ketone bodies are water-soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
(d)
Interpretation:
Whether the molecule β-hydroxybutyrate is a C2, C4, C6 or C8 molecule has to be determined.
Concept introduction:
Ketone bodies are water-soluble molecules which are synthesized from acetyl CoA through the process of ketogenesis. Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
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EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
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- Give the process/pathway where each of the following enzymes is involved. _______________________ a. HMG CoA lyase _______________________ b. HMG CoA reductase _______________________ c. Acetyl CoA carboxylase _______________________ d. Acyl CoA dehydrogenasearrow_forwardFlavonoid undergoes phase II metabolic conversion as it passage through the small intestinal enterocytes and the liver before it is delivered to the general circulation to be available for use by the body.1. What is phase II metabolism?2. Which polyphenol metabolites can be formed?3. How does this affect the biological activity of polyphenols (in the body)?arrow_forwardWhich one of the following will function to inhibit CPT1? A.palmitoyl-CoA B.citrate C propionyl-CoA D.acetyl-CoA E malonyl-CoAarrow_forward
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