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Concept explainers
Interpretation: To determine the two molecules those are needed to initially activate a fatty acid molecule in the oxidation of fatty acids.
Concept introduction: Fatty acids are molecules that are long hydrocarbon chain of
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions.
The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane.
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- The cholesterol synthesized by cells uses which component of the glycolytic pathway as a starting point? a. glucose b. acetyl CoA c. pyruvate d. carbon dioxidearrow_forwardWhich of the following produces the highest number of reducing equivalent molecules per mole of a saturated 10 carbon fatty acid chain in aerobic conditions? A. Oxidation of Malate to Oxaloacetate B. the Electron Transport Chain C. Oxidation of a-Ketoglutarate to Succinyl-COA D. the B-Oxidation "spiral"arrow_forwardWhich of the following is NOT produced during the reactions of acetyl-CoA formation? (only one choice is correct) A. Acetyl CoA B. Electrons C. CO2 D. ATParrow_forward
- Which of the following are the precursors in synthesizing myristic acid? a. 7 malonyl-CoA b. 3 acetyl-CoA, 4 malonyl-CoA c. 1 acetyl-CoA, 6 malonyl-CoA d. 7 acetyl-CoAarrow_forwardPalmitate is a 16-carbon fatty acid. After complete ß-oxidation of one molecule of palmitate, how many molecules of NADH are formed? a. 8 O b. 1 c. 7 O d. 2 O e. 16arrow_forwardMatch the enzyme to the reaction catalysed. Not all the enzymes have to be selected, and an enzyme may be used more than once. v Synthesizes phosphatidic acid A. Glycerol-3-phosphate dehydrogenase v Synthesizes triacylglycerol B. Glycerol kinase v Synthesizes acetoacetyl-CoA C. Acyl-CoA cholesterol acyl transferase v Synthesizes mevalonate D. Lipin v Synthesize 1,2 diacylglycerol E. Acyl transferase v Converts glycerol into glycerol-3-phosphate F. HMG-CoA reductase v Converts dihydroxyacetone phosphate into glycerol-3-phosphate G. Thiolase v Synthesize cholesterol-esterarrow_forward
- CHOOSE THE CORRECT LETTER What major metabolic substrate do ketone bodies convert into so that they enter the metabolic pathway?A. acetyl-CoAB. oxaloacetateC. c02D. pyruvatearrow_forwardWhich of the following reactions correspond to the decarboxylation step during ketone body formation? A. 2 acetyl-CoA → acetoacetyl-CoA B. ß-hydroxybutarate → acetoacetate C. Acetoacetate → acetone D. HMG-CoA → mevalonatearrow_forwardIn fatty acid oxidation, each cycle shortens the fatty acid being catabolised by 2 carbons, producing acetyl CoA and 2 reduced carrier molecules. Complete oxidation of a saturated fatty acid with 18 carbons would produce how many acetyl CoA and reduced carrier molecules? a. 8 acetyl CoA, 8 NADH and 8 FADH2 b. 9 acetyl CoA, 8 NADH and 8 FADH2 c. 8 acetyl CoA, 9 NADH and 9 FADH2 d. 9 acetyl CoA, 9 NADH and 9 FADH2arrow_forward
- Which is co-produced from the conversion of fatty hydroxyacyl CoA to ketoacyl CoA? a. NADH b. FADH2 c. Acetyl COA d. ATP Transamination of glutamate will yield a. asparagine b. glutamine c. Succinyl CoA d. a-ketoglutarate The following amino acids are both glucogenic and ketogenic EXCEPT a. Isoleucine b. Tryptophan c. Leucine d. Tyrosine Which ofthe following is the precursor of fatty acid synthesis? а. Рyruvate b. Malonyl CoA c. Acetyl CoA d. Oxaloacetate • Carboxylation of acetyl CoA to produce malonyl CoA is catalyzed by a. Malonyl CoA carboxylase b. Pyruvate carboxylas c. Pyruvatew dehydrogenase d. Acetyl Co carboxylasearrow_forwardThe rate-limiting step in fatty acid synthesis is: a. The reduction of the acetoacetyl group to a ?-hydroxybutyryl group b. Formation of malonyl-CoA from malonate and coenzyme A. c. Condensation of acetyl-CoA and malonyl-CoA. d. The reaction catalyzed by acetyl-CoA carboxylase.arrow_forwardWhat do the following pathways provide for fatty acid synthesis? A. Citric acid cycle B. Pentose phosphate pathway C. Glycolysis D. Oxidative Phosphorylation. Single line text. give answer in 2-3 linesarrow_forward
- Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
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