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Concept explainers
(a)
Interpretation:
Glucose-6-phosphate is encountered in which of the four processes glycolysis, glycogenesis, glycogenolysis, and gluconeogenesis has to be indicated.
Concept introduction:
In the glycolysis
Gluconeogenesis is an eleven-step pathway in which glucose is produced from non-carbohydrate substances. Glycogenesis is the metabolic pathway that converts glucose-6-phosphate to glycogen. Glycogenolysis is the metabolic pathway that converts glycogen to glucose-6-phosphate.
Glucose-6-phosphate is an activated glucose molecule. The structure of glucose-6-phosphate is as follows:
(b)
Interpretation:
Dihydroxyacetone phosphate is encountered in which of the four processes glycolysis, glycogenesis, glycogenolysis, and gluconeogenesis has to be indicated.
Concept introduction: In the glycolysis metabolic pathway, a glucose molecule breaks down into two pyruvate molecules. Two ATP molecules and NADH reduced coenzymes are produced in the glycolysis pathway.
Gluconeogenesis is an eleven-step pathway in which glucose is produced from non-carbohydrate substances. Glycogenesis is the metabolic pathway that converts glucose-6-phosphate to glycogen. Glycogenolysis is the metabolic pathway that converts glycogen to glucose-6-phosphate.
The structure of dihydroxyacetone phosphate is as follows:
(c)
Interpretation:
Oxaloacetate is encountered in which of the four processes glycolysis, glycogenesis, glycogenolysis, and gluconeogenesis has to be indicated.
Concept introduction:
In the glycolysis metabolic pathway, a glucose molecule breaks down into two pyruvate molecules. Two ATP molecules and NADH reduced coenzymes are produced in the glycolysis pathway.
Gluconeogenesis is an eleven-step pathway in which glucose is produced from non-carbohydrate substances. Glycogenesis is the metabolic pathway that converts glucose-6-phosphate to glycogen. Glycogenolysis is the metabolic pathway that converts glycogen to glucose-6-phosphate.
The structure of oxaloacetate is as follows:
(d)
Interpretation:
UDP-glucose is encountered in which of the four processes glycolysis, glycogenesis, glycogenolysis, and gluconeogenesis has to be indicated.
Concept introduction:
In the glycolysis metabolic pathway, a glucose molecule breaks down into two pyruvate molecules. Two ATP molecules and NADH reduced coenzymes are produced in the glycolysis pathway.
Gluconeogenesis is an eleven-step pathway in which glucose is produced from non-carbohydrate substances. Glycogenesis is the metabolic pathway that converts glucose-6-phosphate to glycogen. Glycogenolysis is the metabolic pathway that converts glycogen to glucose-6-phosphate.
The structure of UDP-glucose is as follows:
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Chapter 24 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- Specify the number of carbon atoms present and the number of phosphate groups present in each of the following glycolysis intermediates (3 points each) 1. Glucose 6 phosphate 2. Fructose 1, 6, phosphate 3. Glyceraldehyde 3-phosphate 4. 3-phospholglycerate 5. Fructose 6 phosphatearrow_forwardWhich of the following is the ninth step of glycolysis? Select one: a. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate b. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate c. Phosphoenolpyruvate is converted to pyruvate d. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate e. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphate f. 3-phosphoglycerate is converted 2-phosphoglycerate g. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate h. Glucose-6-phosphate is converted to Fructose-6-phosphate i. 2-phosphoglycerate is converted to Phosphoenolpyruvate j. Glucose is converted to Glucose-6-phosphatearrow_forwardDuring glycolysis (under anaerobic conditions), for each glucose molecule broken down, how many ATP molecules are used and how many are made in total? A diagram summarizing the different reactions of glycolysis is given below. ATP ADP ATP ADP Glucose Glucose-6-phosphate Fructose-6-phosphate Fructose-1,6-bisphosphate Dihydroxyacetone phosphate 2 (Glyceraldehyde-3-phosphate) Glyceraldehyde- 3-phosphate 2 (1,3-Bisphosphoglycerate) 2 (3-Phosphoglycerate) 2 (2-Phosphoglycerate) 2 H₂O 2 (Phosphoenolpyruvate) 2 (Pyruvate) 2 NAD+ + 2Pi 2 NADH + 2H 2 ADP 2 ATP -2 ADP 2 ATP 2 ATP molecules are used and 2 ATP molecules are made 2 ATP molecules are used and 4 ATP molecules are made O 6 ATP molecules are used and no ATP molecules are made O 4 ATP molecules are used and 2 ATP molecules are made O No ATP molecules are used and 6 ATP molecules are madearrow_forward
- Match the description with the correct enzyme. Descriptions: a. Uses alpha-keto carboxylic acid as a substrate b. Directly transfers cytosolic reducing equivalents into the electron transport chain c. Its activity depends on magnesium ions Options (enzymes): A. Mitochondrial glycerol 3-phosphate dehydrogenase B. Succinate dehydrogenase C. Cytosolic glycerol 3-phosphate dehydrogenase D. Cytochrome oxidase E. Rubisco F. α-ketoglutarate dehydrogenase complexarrow_forwardWhich of the following answer choices correctly describes the function of amylase? Select one: a. Cleaves polysaccharides into glucose, limit dextrins, and maltose b. Cleaves each molecule of glucose into two molecules of pyruvate c. Cleaves monosaccharides into glucose, limit dextrins, and maltose d. Cleaves polysaccharides into amino acids, limit dextrins, and monosaccharides at alpha-1-6 branch pointsarrow_forwardWhich of the following is the third step of glycolysis? Select one: a. Glucose is converted to Glucose-6-phosphate b. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate c. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate d. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate e. 3-phosphoglycerate is converted 2-phosphoglycerate f. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate g. Glucose-6-phosphate is converted to Fructose-6-phosphate h. 2-phosphoglycerate is converted to Phosphoenolpyruvate i. Phosphoenolpyruvate is converted to pyruvate j. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphatearrow_forward
- Determine the number of carbon atoms present and the the total number of phosphate groups present in each of these following intermediates of glycolysis: a. Glyceraldehyde 3-phosphate b. 3-Phosphoglyceratearrow_forwardWhich of the following enzymes is found in gluconeogenesis but not in glycolysis? a. phosphohexose isomerase b. hexokinase c. fructose 1,6-bisphosphatase d. phosphoglycerate kinasearrow_forwardWhich of the following is the fourth step of glycolysis? Select one: a. Phosphoenolpyruvate is converted to pyruvate b. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate c. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate d. Glucose-6-phosphate is converted to Fructose-6-phosphate e. 2-phosphoglycerate is converted to Phosphoenolpyruvate f. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate g. 3-phosphoglycerate is converted 2-phosphoglycerate h. Glucose is converted to Glucose-6-phosphate i. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate j. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphatearrow_forward
- The Glycolytic pathway describes the oxidation of glucose to pyruvate with the generation of ATP and NADH Which of the following 8 statements are correct about the process of Glycolysis? a.Dihydroxyacetone phosphate is isomerized to the aldehyde glyceraldehyde 3-phosphate b. phosphoenolpyruvate is formed from the loss of a hydrogen atom on carbon 2 and a hydroxyl group from carbon 3 c. Glucose transporters only transports phosphorylated glucose d. 2 molecules of NADH is produced from the phosphorylated oxidation of Glyceraldehyde-3-phosphate e. when phosphoenolpyruvate is converted to pyruvate, 1 molecule of ATP is produced f. Fructose-1,6.biphosphate is cleaved by aldolase to form 2 molecules of glyceraldehyde-3-phosphate g. The substrate level phosphorylation of 1,3-biphosphoglycerate yields 2 molecules of ATP h. Glyceraldehyde-3-phosphate loses a hydrogen atom on carbon 1 and gains an oxygen atom i. The ketose sugar glucose-6-phosphate is…arrow_forwardHow many total (NOT NET) molecules of ATP are synthesized from ADP via glycolysis of a single molecule of glucose? Explain by detailing the reactions (steps) involved.arrow_forwardGlycogen synthase may be regulated by covalent modification and/or allosteric control. Label the diagram with the appropriate terms to describe glycogen synthase regulation. Use the following options: Glucose-6-Phospate; Insulin; Fructose-2,6-Bisphosphate; Phosphorylation, Dephosphorylationarrow_forward
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