Concept explainers
(a)
Interpretation: To identify the step in which the
Concept introduction: Glycolysis is the
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
A reactant is defined as the substance that is initially present in the
(b)
Interpretation: To identify the step in which the
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH coenzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
A reactant is defined as the substance that is initially present in the chemical reaction and gets consumed to form a new substance.
(c)
Interpretation: To identify the step in which the
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH coenzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
A reactant is defined as the substance that is initially present in the chemical reaction and gets consumed to form a new substance.
(d)
Interpretation: To identify the step in which the
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH coenzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
A reactant is defined as the substance that is initially present in the chemical reaction and gets consumed to form a new substance.
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Chapter 24 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- Why is the isomerization of glucose-6-phosphate (G6P) to fructose-6-phosphate (F6P) an important step in glycolysis? How is the isomerization of F6P back into G6P prevented?arrow_forward..a) Draw all of the reactions that occur in the aerobic metabolism of glucose that hydrolyze a thiolester bond. In your answer, include complete structural formulae as well as the names of any cofactors, enzymes, reactants and products. b) Explain why the free energy changes that characterize these reactions are so exergonic. Include a figure in your answer. ( c) If you were to completely catabolize 3 molecules of glucose under aerobic conditions, what would the ATP yield be as a result of the reactions that you've drawn above?arrow_forwardWhat is the citric acid cycle? Provide a schematic diagram of the citric acid cycle with chemical structures of each compound in the cycle. Indicate the cofactors and products at each step as well as the name of each of the enzymes involved.arrow_forward
- The overall reactions for gluconeogenesis and glycolysis are given below. What is the energy cost (in ATP equivalents) of transforming one molecule of glucose to pyruvate (via glycolysis) and back to glucose (via gluconeogenesis)? Gluconeogenesis: 2 pyruvate + 4 ATP + 2 GTP + 2NADH + 4H₂O Glycolysis: Glucose + 2ADP + 2P₁ + 2NAD+ - 2 pyruvate + 2ATP + 2NADH + 2H+ + 2H₂000 Select one: O a. 2 ATP O b. 4 ATP O c. 6 ATP O d. 8 ATP Prev Page glucose + 4ADP + 2GDP + 2P₁ + 2NAD+ + 2H+ MI 21 22 00:508D DAD 1=1 SE 30: DONDOK 23 24 25 26 27 28 29 30 Report question issue B Next Page Garrow_forwarda) What happens during the two phases of glycolysis? Write the reaction steps of glycolysis showing their the enzymes that catalyze the reactions. (Draw only the structure of the first and last product) b) How many net moles of ATP can be synthesized from each mol of glucose? c) The overall equation for glycolysis?arrow_forwardWhy is there such a large range of ∆G for the second step of glycolysis?arrow_forward
- The standard state free energy change for Step 4 of glycolysis (where an aldolase enzyme splits fructose 1,6-bisphosphate into GAP and DHAP) is +23.8 kJ/mol. Yet, glycolysis still proceeds spontaneously in the vast majority of cells. Why does this step in particular proceed spontaneously under typical cellular conditions?arrow_forwardWhat is the standard free-energy change, ∆G°, under physiological conditions(E. coli grows in the human gut, at 37 °C) for the following reaction?Glucose + ATP → glucose 6-phosphate + ADParrow_forwardThe reaction pictured is an oxidation-reduction reaction in the citric acid cycle in which the energy-carrier molecule NADH is generated. Identify which molecule in the reaction will be oxidized and which molecule will be reduced. Place a single answer choice in each box. COO- HO-C-H H-C-H COO- Malate NAD+ NADH + H+ Oxidized malate oxaloacetate COO- H-C-H ī COO- Oxaloacetate Reduced NADH NAD+arrow_forward
- Consider the following list of phosphorylated compounds with their free energy changes of phosphate hydrolysis: Glucose-1-phosphate (-5.0 kcal/mol), PEP (-14.8 kcal/mole), 1,3-bisphosphoglycerate (-11.8 kcal/mole) and Glucose-6-Phosphate (-3.3 kcal/mol). Given that the free energy change of ATP hydrolysis is -7.3 kcal/mole, which of these molecules be directly synthesized by the transfer of a phospho- group from ATP? 1,3-bisphosphoglycerate Glucose-6-phosphate All of those phosphorylated compounds. PEP Glucose-1-phosphatearrow_forwardglycerol 3-phosphate forms the backbone of glycerosphospholipids. what 3-carbon intermediate in the glycolysis pathway is the immediate precursor of glycerol 3-phosphate?arrow_forwardWhich statement best describes the reason why some of the reactions of glycolysis cannot be run in reverse in gluconeogenesis? 1) The last reactions occur in mitochondria and reactions there can never be reversed. 2) Glycolysis includes isomerization reactions and these can never be reversed. 3) There are some allaşteric enzymes and allosteric enzymes can never be reversed. 4) Some reactions have such large negative free energy changes that they can never be reversed under cellular conditions. Oarrow_forward
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