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Concept explainers
Interpretation: To identify the substances that are participants in the reactions encircled by the Cori cycle.
Concept introduction: Glucose is converted to pyruvate by glycolysis
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
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Chapter 24 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- Which of the following statements are TRUE?Multiple answers are accepted for this question a .Two molecules of CO2 are produced each time a molecule of Acetyl-CoA is oxidized. b. During the first turn of the TCA Cycle the carbon atoms of Acetyl-CoA become CO2. c. The number of molecules of ATP that can be produced in the Citric Acid Cycle by substrate level phosphorylation of ADP from two molecules of Acetyl-CoA is 30. d. Fumarate contains a trans double bond. The cis isomer of Fumarate is Maleate which cannot serve as carbon source for a cell. e. Lack of O2 would decrease the rate of the Citric Acid Cycle in red blood cells. f. If a potent inhibitor of Succinyl-CoA Synthetaseis is applied to liver cells both energy production and synthesis of carbohydrate would be affected. g. The overall chemical changes that occur during one complete turn of the Citric Acid Cycle is the complete oxidation of one molecule of Acetyl-CoA plus the production of two molecules of CO2 plus the…arrow_forwardWhich of the following enzymes do not catalyze a reaction in the citrate cycle that produces CO2 as a product? Choose one or more: OA. isocitrate dehydrogenase OB. fumarase L C. succinate dehydrogenase O D. succinyl-CoA synthetasearrow_forwardWhich of the following are the precursors in synthesizing myristic acid? a. 7 malonyl-CoA b. 3 acetyl-CoA, 4 malonyl-CoA c. 1 acetyl-CoA, 6 malonyl-CoA d. 7 acetyl-CoAarrow_forward
- Which of the following is NOT produced during the reactions of acetyl-CoA formation? (only one choice is correct) A. Acetyl CoA B. Electrons C. CO2 D. ATParrow_forwardPyruvate dehydrogenase complex is the key enzyme that regulates the TCA cycle. De-phosphorylation of this enzyme by phospho-protein phosphatase makes it active. Which of the following compounds is expected to activate phospho-protein phosphatase? Acetyl COA a. O b. NADH Ca²+ O C. O d. ATParrow_forwardMatch the item to each step in the Krebs Cycle. Write your answers on the Google Form. isocitrate f. Oxaloacetate a. b. succinate g. Sulfur NAD* h. a-ketoglutarate fumarate C. d. malate i. succinyl-CoA j. ATP e. What molecule combines with acetyl-CoA and then releases CoA? 66. What molecule is oxidized by NAD+ to become a 5- carbon compound? 67. What molecule is oxidized by NAD+ to become a 4- carbon compound? 68. 69. What 4-carbon molecule is formed when combined with COA? 70. What molecule is produced when CoA is released? 71. What molecule is formed when GTP is oxidized to form GDP? 72. What atom is the bridge that connects to CoA? 73. What molecule is formed when FAD is reduced? 74. What molecule is formed with the addition of H,O? 75. Which molecule must be reduced so that oxaloacetate is formed? Match the product to the process. Write your answer on the Google Form. GTP f. CO, а. b. phosphofructinase NADH* + CO, g. Citrate formed. c. h. ATP d. Co-A i. Isocitrate HO j- Pyruvate e.…arrow_forward
- Which of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenasearrow_forwardIn Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C. lactate only D. ethanol onlyarrow_forwardWhich of the following enzymes is the key regulatory step in glycolysis? Phosphofructiokinase-1 is the answer. Explain? A. Phosphoglucose Isomerase B. Phosphofructokinase-1 C. Pyruvate Kinase D. Hexokiase E. Phosphofructokinase-2 ...Why is Phosphoglucose Isomerase wrong?arrow_forward
- Which of the following is the chemical end product of fatty-acids metabolized in the beta-oxidation pathway? Select one: a. Beta-carotine b. Free-radicals c. Lactic acid d. Acetyl-CoA e. Pyruvatearrow_forwardA patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor Barrow_forwardWhich of the following reactions is reversible and irreversible? Why? a. Pyruvate + β-hydroxybutyrate → lactate + acetoacetate b. Malate + pyruvate → oxaloacetate + lactate c. Acetaldehyde + succinate → ethanol + fumarate d. Pyruvate + NADH + H+ → lactate NAD+ e. Acetoacetate + NADH + H+ → β-hydroxybutyrate + NAD+ f. Malate + NAD+ → oxaloacetate + NADH + H+arrow_forward
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