EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
7th Edition
ISBN: 8220100853180
Author: STOKER
Publisher: CENGAGE L
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Chapter 24, Problem 24.40EP
Interpretation Introduction
Interpretation: To identify the two methods by which the supply of
Concept introduction: In the glycolysis
Lactate dehydrogenase enzymes convert pyruvate to lactate under anaerobic conditions in the human body. This anaerobic reduction of pyruvate to form lactate by enzymes is called lactate fermentation.
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Consider the net summary equation for glycolysis. Suppose 13 molecules of glucose enter glycolysis. Calculate the number of molecules produced or used (a-d) upon completion of glycolysis utilizing all 13 glucose molecules. (a) # P; used (b) # pyruvates produced (c) # NADH produced (d) #ADP used.
DCCD (diocyclohexylcarbodiimide) inhibits oxidative phosphorylation when the substrate is mitochondrial NADH. DCCD is a drug that binds to ATP synthase and blocks proton transport through the ion channel.
a) Explain what the consequences of DCCD on cellular energy production are.
b) Suggest at least one other cellular effect of DCCD and explain this effect.
Organisms growing anaerobically cannot perform glycolysis for long without
reducing the pyruvate from glycolysis into another compound, most commonly to
lactate or to ethanol plus CO2.
Which of the following provides the best explanation for sustaining anaerobic
glycolysis?
O Lactic acid has to be reduced to regenerate NADH
Pyruvate has to be reduced to regenerate NADH
Pyruvate has to be reduced to regenerate NAD+
Lactic acid has to be reduced to regenerate NAD+
Chapter 24 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
Ch. 24.1 - The primary site within the human body where...Ch. 24.1 - What is the first site within the human body where...Ch. 24.1 - What effect does gastric juice in the stomach have...Ch. 24.1 - Prob. 4QQCh. 24.1 - Which of the following substances is needed for...Ch. 24.2 - Prob. 1QQCh. 24.2 - Prob. 2QQCh. 24.2 - Prob. 3QQCh. 24.2 - Prob. 4QQCh. 24.2 - Prob. 5QQ
Ch. 24.2 - Prob. 6QQCh. 24.2 - Prob. 7QQCh. 24.3 - Prob. 1QQCh. 24.3 - Prob. 2QQCh. 24.3 - Prob. 3QQCh. 24.3 - Prob. 4QQCh. 24.3 - Accumulation of which of the following substances...Ch. 24.4 - Prob. 1QQCh. 24.4 - The net yield of ATP for the complete oxidation of...Ch. 24.4 - Prob. 3QQCh. 24.5 - Prob. 1QQCh. 24.5 - Prob. 2QQCh. 24.5 - Prob. 3QQCh. 24.6 - Prob. 1QQCh. 24.6 - Prob. 2QQCh. 24.6 - Prob. 3QQCh. 24.6 - Which of the following statements about ATP...Ch. 24.6 - Prob. 5QQCh. 24.7 - Prob. 1QQCh. 24.7 - Prob. 2QQCh. 24.8 - Prob. 1QQCh. 24.8 - Prob. 2QQCh. 24.8 - Prob. 3QQCh. 24.9 - Which of the following hormones promotes the...Ch. 24.9 - Which of the following pairs of hormones increases...Ch. 24.10 - Prob. 1QQCh. 24.10 - Prob. 2QQCh. 24.10 - Prob. 3QQCh. 24 - Where does carbohydrate digestion begin in the...Ch. 24 - Very little digestion of carbohydrates occurs in...Ch. 24 - Prob. 24.3EPCh. 24 - Prob. 24.4EPCh. 24 - Prob. 24.5EPCh. 24 - Prob. 24.6EPCh. 24 - Prob. 24.7EPCh. 24 - Prob. 24.8EPCh. 24 - Prob. 24.9EPCh. 24 - Prob. 24.10EPCh. 24 - Prob. 24.11EPCh. 24 - Prob. 24.12EPCh. 24 - Prob. 24.13EPCh. 24 - Prob. 24.14EPCh. 24 - Prob. 24.15EPCh. 24 - Prob. 24.16EPCh. 24 - Prob. 24.17EPCh. 24 - Prob. 24.18EPCh. 24 - Prob. 24.19EPCh. 24 - Prob. 24.20EPCh. 24 - Prob. 24.21EPCh. 24 - Prob. 24.22EPCh. 24 - Prob. 24.23EPCh. 24 - Prob. 24.24EPCh. 24 - Prob. 24.25EPCh. 24 - Prob. 24.26EPCh. 24 - Prob. 24.27EPCh. 24 - Prob. 24.28EPCh. 24 - Prob. 24.29EPCh. 24 - Prob. 24.30EPCh. 24 - Prob. 24.31EPCh. 24 - Prob. 24.32EPCh. 24 - Prob. 24.33EPCh. 24 - Prob. 24.34EPCh. 24 - Prob. 24.35EPCh. 24 - Prob. 24.36EPCh. 24 - Prob. 24.37EPCh. 24 - Prob. 24.38EPCh. 24 - Prob. 24.39EPCh. 24 - Prob. 24.40EPCh. 24 - Prob. 24.41EPCh. 24 - Prob. 24.42EPCh. 24 - Prob. 24.43EPCh. 24 - Prob. 24.44EPCh. 24 - Prob. 24.45EPCh. 24 - Prob. 24.46EPCh. 24 - Prob. 24.47EPCh. 24 - Prob. 24.48EPCh. 24 - Prob. 24.49EPCh. 24 - Prob. 24.50EPCh. 24 - Prob. 24.51EPCh. 24 - Prob. 24.52EPCh. 24 - Prob. 24.53EPCh. 24 - Prob. 24.54EPCh. 24 - Prob. 24.55EPCh. 24 - Prob. 24.56EPCh. 24 - Prob. 24.57EPCh. 24 - Prob. 24.58EPCh. 24 - Prob. 24.59EPCh. 24 - Prob. 24.60EPCh. 24 - Prob. 24.61EPCh. 24 - Prob. 24.62EPCh. 24 - Prob. 24.63EPCh. 24 - Prob. 24.64EPCh. 24 - Prob. 24.65EPCh. 24 - The liver, but not the brain or muscle cells, has...Ch. 24 - Prob. 24.67EPCh. 24 - Prob. 24.68EPCh. 24 - Prob. 24.69EPCh. 24 - Prob. 24.70EPCh. 24 - Prob. 24.71EPCh. 24 - Prob. 24.72EPCh. 24 - Prob. 24.73EPCh. 24 - Prob. 24.74EPCh. 24 - Prob. 24.75EPCh. 24 - Prob. 24.76EPCh. 24 - Prob. 24.77EPCh. 24 - Prob. 24.78EPCh. 24 - Prob. 24.79EPCh. 24 - Prob. 24.80EPCh. 24 - Prob. 24.81EPCh. 24 - Prob. 24.82EPCh. 24 - Prob. 24.83EPCh. 24 - Prob. 24.84EPCh. 24 - Prob. 24.85EPCh. 24 - Prob. 24.86EPCh. 24 - Prob. 24.87EPCh. 24 - Prob. 24.88EPCh. 24 - Prob. 24.89EPCh. 24 - Prob. 24.90EPCh. 24 - Prob. 24.91EPCh. 24 - Prob. 24.92EPCh. 24 - Prob. 24.93EPCh. 24 - Prob. 24.94EPCh. 24 - Prob. 24.95EPCh. 24 - Prob. 24.96EPCh. 24 - Prob. 24.97EPCh. 24 - Prob. 24.98EPCh. 24 - Prob. 24.99EPCh. 24 - Prob. 24.100EPCh. 24 - Prob. 24.101EPCh. 24 - Prob. 24.102EPCh. 24 - Prob. 24.103EPCh. 24 - Prob. 24.104EPCh. 24 - Prob. 24.105EPCh. 24 - Prob. 24.106EPCh. 24 - Prob. 24.107EPCh. 24 - Prob. 24.108EPCh. 24 - Prob. 24.109EPCh. 24 - Prob. 24.110EPCh. 24 - Prob. 24.111EPCh. 24 - Prob. 24.112EPCh. 24 - Prob. 24.113EPCh. 24 - Prob. 24.114EPCh. 24 - Prob. 24.115EPCh. 24 - Compare the biological functions of glucagon and...Ch. 24 - Prob. 24.117EPCh. 24 - Prob. 24.118EP
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- Name the enzymes that catalyse (a) substrate-level phosphorylation and (b) coupled reactions during glycolysis and the TCA cycle.arrow_forwarda) Using full chemical structures of substrates and products, draw the two possible pyruvate reduction pathways that regenerate NAD+ from NADH in the absence of oxygen gas. Give names of all compounds and enzymes involved. b) Draw the step in glycolysis that requires at least one of the above pathways to be functional in the absence of oxygen. Give names of all compounds and enzymes involved.arrow_forwardWhat is the overall net reaction of glycolysis? C6H12O6 + 2 NADH + 2 P₁ + 2 ATP --> 2 C3H3O3 + 2 NAD+ + 2 H+ + 2 H₂O + 2 ADP C6H12O6 + 2 NAD+ + 4 P₁ + 4 ADP --> 2 C3H3O3 + 2 NADH + 2 H+ + 2 H₂O + 4 ATP Glucose + 2 NAD+ + 2 P₁ + 2 ADP --> 2 C3H3O3 + 2 NADH + 2 H+ + 2 H₂O + 2 ATP Glucose + 2 FAD + 2 P; + 2 ADP --> 2 Pyruvate + 2 FADH₂ + 2 H+ + 2 H₂O + 2 ATP C6H12O6 + 2 NAD+ + 2 P₁ + 2 ADP --> Pyruvate + 2 NADH + 2 H+ + 2 H₂O + 2 ATParrow_forward
- Which mechanisms may be used to reverse a high NADH:NAD+ ratio in the cytosol under anaerobic conditions?arrow_forwardDraw OUT THE arrow pushing reaction mechanism for the following steps of glycolysis: SHOW/IDENTIFY the arrow pushing mechanism in at least 2 steps. CH,OPO CH,OH hexokinase 2+ H H H H H H ОН + ATP OH H ADP + H+ H ОН + НО HO OH H ОН H ОН Glucose-6-phosphate (G6P) Glucosearrow_forwardPhosphofructokinase is considered to be the enzyme responsible for controlling the rate-limiting step of the glycolytic pathway. Why would this step be considered rate-limiting step? Explain with reference to the feedback mechanisms that are occurring in cell respiration.arrow_forward
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- In order to metabolize lactose, most infants express the enzyme lactase in their intestines. How many pyruvate molecules and NADH molecules can be generated in glycolysis from one lactose molecule? Please explain. How many ATP molecules will be used and generated by 1 lactose molecule? Please explain.arrow_forwardExplain how cytosolic pyruvate from glycolysis results in formation of ATP in mitochondria. Please highlight stages where substrate-level Phosphorylation and Oxidative Phosphorylation occur.arrow_forwardWhat is the stoichiometry of the synthesis of (a) ribose 5-phosphate from glucose 6-phosphate without the concomitant generation of NADPH? (b) NADPH from glucose 6- phosphate without the concomitant formation of pentose sugars?arrow_forward
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