Concept explainers
(a)
Interpretation: To identify the name of the missing substance in the following word equation.
Concept introduction: Glycolysis is the
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
(b)
Interpretation: To identify the name of the missing substance in the following word equation.
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH reduced coenzymes. The process of glycolysis is a ten-step process in which each step is catalyzed by enzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
In the cleavage reaction, the carbon-carbon bond is cleaved to form a new bond between carbon and oxygen atom.
(c)
Interpretation: To identify the name of the missing substance in the following word equation.
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH reduced coenzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
In the phosphorylation reaction, the molecule is attached to the phosphoryl group. The transfer of a phosphoryl group
(d)
Interpretation: To identify the name of the missing substance in the following word equation.
Concept introduction: Glycolysis is the metabolic pathway that breaks down a glucose molecule and converts it into two pyruvate molecules along with the production of two ATP molecules and NADH reduced coenzymes.
The block diagram to represent an overview of glycolysis is as follows:
From the above diagram, it is concluded that in the overall process of glycolysis, two stages are present.
a) Steps 1 to 3 represents a six-carbon stage
b) Steps 4 to 10 represent a three-carbon stage
In the isomerization reaction, a molecule transformed itself to another molecule, having the same number of atoms with a different arrangement.
Enzymes are defined as specialized proteins that act as biological catalysts. Enzymes accelerate the biochemical reactions to produce the substances that are needed for cells for their proper functioning and are very specific to their action.
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EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- Match the enzyme to the reaction catalysed. Not all the enzymes have to be selected, and an enzyme may be used more than once. v Synthesizes phosphatidic acid A. Glycerol-3-phosphate dehydrogenase v Synthesizes triacylglycerol B. Glycerol kinase v Synthesizes acetoacetyl-CoA C. Acyl-CoA cholesterol acyl transferase v Synthesizes mevalonate D. Lipin v Synthesize 1,2 diacylglycerol E. Acyl transferase v Converts glycerol into glycerol-3-phosphate F. HMG-CoA reductase v Converts dihydroxyacetone phosphate into glycerol-3-phosphate G. Thiolase v Synthesize cholesterol-esterarrow_forwardCHOOSE THE CORRECT LETTER Which of the following reactions does NADH act as coenzyme?A. "glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate"B. pyruvate to acetyl-CoAC. isocitrate to a-ketoglutarateD. pyruvate to lactatearrow_forwardPair the reactions mentioned on the left with the names of the enzymes on the right. 1,3-bisphosphoglycerate to 3-phosphoglycerate [ Choose ] [ Choose ] 3-Phosphoglycerate to 2-Phosphoglycerate Phosphoglucoisomerase Phosphoglycerate kinase Pyruvate Kinase Glucose-6-P to Fructose-6-P Phosphoglyceromutase Triose phosphate isomerase Dihydroxyacetone phosphate to Glyceraldehyde [ Choose ] 3-Phosphate Phosphoenolpyruvate to Pyruvate [Choose ]arrow_forward
- CHOOSE THE CORRECT LETTER. Which of the following reactions require ATP in glycolysis?A. glucose-6-phosphate to fructose-6-phosphateB. fructose-1,6-bisphosphate to glyceraldehyde-3-phosphateC. 3-phosphoglycerate to 2-phosphoglycerateD. fructose-6-phosphate to fructose-1,6-bisphosphatearrow_forwardWhich of the following reactions is reversible and irreversible? Why? a. Pyruvate + β-hydroxybutyrate → lactate + acetoacetate b. Malate + pyruvate → oxaloacetate + lactate c. Acetaldehyde + succinate → ethanol + fumarate d. Pyruvate + NADH + H+ → lactate NAD+ e. Acetoacetate + NADH + H+ → β-hydroxybutyrate + NAD+ f. Malate + NAD+ → oxaloacetate + NADH + H+arrow_forwardCHOOSE THE CORRECT LETTER What type of reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase?A.phosphorylationB.reductionC. isomerizationD. oxidationarrow_forward
- During glycolysis (under anaerobic conditions), for each glucose molecule broken down, how many ATP molecules are used and how many are made in total? A diagram summarizing the different reactions of glycolysis is given below. ATP ADP ATP ADP Glucose Glucose-6-phosphate Fructose-6-phosphate Fructose-1,6-bisphosphate Dihydroxyacetone phosphate 2 (Glyceraldehyde-3-phosphate) Glyceraldehyde- 3-phosphate 2 (1,3-Bisphosphoglycerate) 2 (3-Phosphoglycerate) 2 (2-Phosphoglycerate) 2 H₂O 2 (Phosphoenolpyruvate) 2 (Pyruvate) 2 NAD+ + 2Pi 2 NADH + 2H 2 ADP 2 ATP -2 ADP 2 ATP 2 ATP molecules are used and 2 ATP molecules are made 2 ATP molecules are used and 4 ATP molecules are made O 6 ATP molecules are used and no ATP molecules are made O 4 ATP molecules are used and 2 ATP molecules are made O No ATP molecules are used and 6 ATP molecules are madearrow_forwardIndicate the general type of enzyme that mediates each glycolysis reaction depicted below. (e.g. Transferase, Oxidoreductase, Kinase, Hydrolase, Lyase, or Isomerase) iii. O H Glyceraldehyde-3-phosphate → 1,3-Bisphosphoglycerate H-C-OH + NAD CH₂O-P + P₁ H-O- -C-H Glucose →→ Glucose-6-phosphate H b 0 OH HO OH H-C- 0 -H HO- H ОН H-C-OH + NADH +H+ CH₂O P P ATP ADP 1 H (P-O- -C- H H HO OH 2-Phosphoglycerate → Phosphoenolpyruvate 0 OH H ОН -O~(P) + HOHarrow_forwardIn class, I mentioned that fructose is metabolized differently in the liver compared to glucose. Refer to the figure shown below to calculate the number ofATPs you would expect from the metabolism of fructose in the liver. Show your work! Fructokinase Fructose Fructose-1-P АТР ADP Aldolase B Dihydroxy- acetone phosphate Glyceraldehyde АТР Triose kinase Triose phosphate isomerase ADP 4 - Glyceraldehyde-3-P Glycolysis Руruvate Acetyl-CoA Fatty acids and triglyceridesarrow_forward
- The reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase involves two "sub-reactions", one of which is unfavourable. How is the energy barrier of this unfavourable sub reaction overcome? A. through the formation and hydrolysis of a thioester bond using a cysteine molecule in the enzyme B. through the hydrolysis of an ATP molecule C. through the hydrolysis of a thioester bond in the substrate molecule D. the enzyme catalyzes the formation of a thioester bond E. none of these explanations describe how the energy barrier is overcome Please answer asaparrow_forwardWhich class of enzymes catalyzes the following reactions? CH2- CH2- CH2 H2- C- CH2 AST CH2-C CH2 CH-NH + C=O + C=0 + CH-NH ČO0 Čo0 ČO0 ČO0" Aspartate Oxoglutarate Oxaloacetate Glutamate Select one: a. Oxidoreductase O b. Isomerase O c. Ligase d. Transferasearrow_forwardThe Glycolytic pathway describes the oxidation of glucose to pyruvate with the generation of ATP and NADH Which of the following 8 statements are correct about the process of Glycolysis? a.Dihydroxyacetone phosphate is isomerized to the aldehyde glyceraldehyde 3-phosphate b. phosphoenolpyruvate is formed from the loss of a hydrogen atom on carbon 2 and a hydroxyl group from carbon 3 c. Glucose transporters only transports phosphorylated glucose d. 2 molecules of NADH is produced from the phosphorylated oxidation of Glyceraldehyde-3-phosphate e. when phosphoenolpyruvate is converted to pyruvate, 1 molecule of ATP is produced f. Fructose-1,6.biphosphate is cleaved by aldolase to form 2 molecules of glyceraldehyde-3-phosphate g. The substrate level phosphorylation of 1,3-biphosphoglycerate yields 2 molecules of ATP h. Glyceraldehyde-3-phosphate loses a hydrogen atom on carbon 1 and gains an oxygen atom i. The ketose sugar glucose-6-phosphate is…arrow_forward
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